生体内機能グレード抗体
I生体内機能グレード抗体
アッセイジニーin vivo機能性グレード抗体は、in vitro機能性試験だけでなく、翻訳および臨床前の動物研究にも使用できる高純度低エンドトキシンモノクローナル抗体です。 これらの抗体は検出可能な浸出性タンパク質Aまたは凝集体がなく、エンドトキシンのレベルが非常に低く、純度が98%以上で業界最高品質基準を持っています。
Assay Genieの生体内抗体は、cGMPとISO 9001:2015 / ISO 13485:2015認証施設で生産され、病原体がないことを理由に動物への注射に使用できます（IDEX Impact IPCRマウス病原体プロファイル）。
この範囲の低および超低エンドトキシン抗体は、ELISA、FC、ICC、IHC-PE、IHC-FF、IP、WB、ELISpot、CODX®&CyTOF®などの機能性研究に使用するためにテストされています。
抗体は1mg、5mg、25mg、50mgおよび100mgのパックサイズを含む柔軟なパックサイズで提供され、要求に応じてカスタムパッケージも使用できます。
カタログには、 PD-1 [clone RMP1-14], PD-L1 (B7-H1) [clone 10F.9G2], そして CTLA-4 [9H10], 免疫細胞の枯渇の主な標的と同様に 例えば CD4, CD8 その他いろいろ。
業界トップクラスの品質
| 低エンドトキシン | 私たちの生体内抗体は、エンドトキシンレベルが低く、検出可能な浸出性タンパク質Aまたは凝集物がない最高品質基準を持っています。 | |
| 高純度 | マルチステッププロセスで精製し、ロット間の高い再現性を確保するために広範囲なQCを実施する。 | |
| 製剤 | 保存料、安定剤、キャリアタンパク質なし。 滅菌済み PBS に K+ または Ca2+ が含まれていません。. | |
| 包括的 | 200以上の機能性グレードの抗体を研究用に使用。 |
アプリケーション
| 生体機能研究 | mAbsが腫瘍の成長と癌の進行に与える影響をテストする。 免疫系を操作するためのT細胞やB細胞などの枯渇 | |
| 試験管内アッセイ | 遮断、中和または活性化などのin vitro機能検査。 細胞シグナル伝達経路の解明 | |
| テスト済みアプリケーション | コストシミュレーション, 細胞枯渇, 中和, ブロッキング, ELISA, FC、ICC、IHC-PE、IHC-FF、IP、WB、CODEX®, CyTOF® |
すべて参照
フルレンジ
免疫チェックポイントとがん生物学
免疫チェックポイントとがん生物学
| Product Name | Reactivity | Clone | Application | Endotoxin Level |
|---|---|---|---|---|
| PD-1 [29F.1A12] In Vivo Antibody | Mouse | 29F.1A12 | B, CODEX®, CyTOF®, FC, IHC FF, WB | Low Endotoxin |
| PD-1 [29F.1A12] In Vivo Antibody | Mouse | 29F.1A12 | B, CODEX®, CyTOF®, FC, IHC FF, WB | Ultra Low Endotoxin |
| PD-1 [RMP1-14] In Vivo Antibody | Mouse | RMP1-14 | B, FA, WB | Low Endotoxin |
| PD-1 [RMP1-14] In Vivo Antibody | Mouse | RMP1-14 | B, FA, WB | Ultra Low Endotoxin |
| PD-L2 In Vivo Antibody | Mouse | TY25 | FC, IHC FF, IP, WB | Low Endotoxin |
| PD-L1 (B7-H1) [10F.9G2] In Vivo Antibody | Mouse | 10F.9G2 | B, CODEX®, FC, IHC FF, WB | Low Endotoxin |
| PD-L1 (B7-H1) [10F.9G2] In Vivo Antibody | Mouse | 10F.9G2 | B, CODEX®, FA, IHC FF, WB | Ultra Low Endotoxin |
| PD-L2 (CD273) In Vivo Antibody | Mouse/Human | 3.2.B8 | B, FC, WB | Ultra Low Endotoxin |
| PD-L2 (CD273) In Vivo Antibody | Mouse/Human | 3.2.B8 | B, FC | Low Endotoxin |
| CTLA-4 [9H10] In Vivo Antibody | Mouse | 9H10 | B, WB | Low Endotoxin |
| CTLA-4 [9H10] In Vivo Antibody | Mouse | 9H10 | B, WB | Ultra Low Endotoxin |
| CTLA-4 (CD152) In Vivo Antibody | Mouse | UC10-4F10-11 | FA, FC, IP, WB | Low Endotoxin |
| CTLA-4 (CD152) In Vivo Antibody | Mouse | UC10-4F10-11 | FA, FC, IP, WB | Ultra Low Endotoxin |
| CTLA-4 [9D9] In Vivo Antibody | Mouse | 9D9 | FA, WB | Low Endotoxin |
| CTLA-4 [9D9] In Vivo Antibody | Mouse | 9D9 | FA, WB | Ultra Low Endotoxin |
| CD28 In Vivo Antibody | Mouse | 37.51 | B, Costim, CyTOF®, FC, IHC FF, IP, WB | Low Endotoxin |
| CD28 In Vivo Antibody | Mouse | 37.51 | B, Costim, CyTOF®, FA, IP, WB | Ultra Low Endotoxin |
| 4-1BB In Vivo Antibody | Mouse | 3H3 | ELISA, FA, WB | Low Endotoxin |
| 4-1BB In Vivo Antibody | Mouse | 3H3 | ELISA, FA, WB | Ultra Low Endotoxin |
| CD120a (TNFR1) [55R-170] In Vivo Antibody | Mouse | 55R-170 | B, IP, WB | Low Endotoxin |
| CD120a (TNFR1) [55R-593] In Vivo Antibody | Mouse | 55R-593 | IP, WB | Low Endotoxin |
| CD120a (TNFR1) [55R-170] In Vivo Antibody | Mouse | 55R-170 | B, FC, IP, WB | Ultra Low Endotoxin |
| CD120a (TNFR1) [55R-593] In Vivo Antibody | Mouse | 55R-593 | FC, IP, WB | Ultra Low Endotoxin |
| CD19 In Vivo Antibody | Mouse | 1D3 | B, CODEX®, Depletion, FC, IHC FF, IP, WB | Low Endotoxin |
| CD19 In Vivo Antibody | Mouse | 1D3 | B, CODEX®, Depletion, FC, IHC FF, IP, WB | Ultra Low Endotoxin |
| CD209b In Vivo Antibody | Mouse | 22D1 | B, FC, IHC FF, WB | Low Endotoxin |
| CD209b In Vivo Antibody | Mouse | 22D1 | B, FC, IHC FF, WB | Ultra Low Endotoxin |
| CD278 (ICOS) In Vivo Antibody | Mouse | 7E.17G9 | B, FA, WB | Low Endotoxin |
| CD278 (ICOS) In Vivo Antibody | Mouse | 7E.17G9 | B, FA, WB | Ultra Low Endotoxin |
| CD40 In Vivo Antibody | Mouse | FGK45 | Act, FA, FC | Low Endotoxin |
| CD40 [FGK45] In Vivo Antibody | Mouse | FGK45 | Act, FA, WB | Ultra Low Endotoxin |
| CD70 In Vivo Antibody | Mouse | TAN1-7 | B, ELISA, FA, FC, IF | Low Endotoxin |
| CD80 In Vivo Antibody | Mouse | 16-10A1 | B, CyTOF®, IP, WB | Low Endotoxin |
| CD80 In Vivo Antibody | Mouse | 16-10A1 | B, CyTOF®, IP, WB | Ultra Low Endotoxin |
| CD86 In Vivo Antibody | Mouse | GL1 | B, WB | Low Endotoxin |
| CD86 In Vivo Antibody | Mouse | GL1 | B, ELISA, WB | Ultra Low Endotoxin |
| CD370 In Vivo Antibody | Mouse | 1F6 | FC, IF, WB | Low Endotoxin |
| GM-CSF In Vivo Antibody | Mouse | MP1-22E9 | N, WB | Low Endotoxin |
| GM-CSF In Vivo Antibody | Mouse | MP1-22E9 | N, WB | Ultra Low Endotoxin |
| CD127 (IL-7Rα) In Vivo Antibody | Mouse | A7R34 | B, CyTOF®, FA, FC, IF Staining, IHC FF, IP, WB | Low Endotoxin |
| CD223 (LAG-3) In Vivo Antibody | Mouse | C9B7W | B, FA, IP, WB | Low Endotoxin |
| Ly-6G In Vivo Antibody | Mouse | 1A8 | CODEX®, CyTOF®, Depletion, FC, IHC FF, WB | Low Endotoxin |
| Ly-6G In Vivo Antibody | Mouse | 1A8 | CODEX®, CyTOF®, Depletion, FC, IHC FF, WB | Ultra Low Endotoxin |
| Ly-6G/Ly-6C (Gr-1) In Vivo Antibody | Mouse | RB6-8C5 | CyTOF®, Depletion, IHC FF, IP, WB | Low Endotoxin |
| Ly-6G/Ly-6C (Gr-1) In Vivo Antibody | Mouse | RB6-8C5 | CyTOF®, Depletion, FC, IHC FF, IHC FFPE, IP, WB | Ultra Low Endotoxin |
| TGF-β1, 2, 3 In Vivo Antibody | Human, Mouse | 1D11.16.8 | IHC, N, WB | Ultra Low Endotoxin |
| CD366 (Tim-3) In Vivo Antibody | Mouse | RMT3-23 | B, CODEX®, FC, IF Staining, IHC, IHC FF | Low Endotoxin |
接着と移行
接着と移行
| Product Name | Reactivity | Clone | Application | Endotoxin Level |
|---|---|---|---|---|
| CD11a In Vivo Antibody | Human | 38 | Costim, FC, WB | Low Endotoxin |
| CD11a In Vivo Antibody | Human | 38 | Costim, FC, WB | Ultra Low Endotoxin |
| CD11a [FD441.8] In Vivo Antibody | Mouse | FD441.8 | FA, FC, WB | Low Endotoxin |
| CD11a [FD441.8] In Vivo Antibody | Mouse | FD441.8 | FC | Ultra Low Endotoxin |
| CD11b In Vivo Antibody | Human | ICRF44 | CODEX®, FC, IF Staining, IHC FF | Low Endotoxin |
| CD11b In Vivo Antibody | Human | ICRF44 | CODEX®, FC, IF Staining, IHC FF | Ultra Low Endotoxin |
| CD11c In Vivo Antibody | Human | 3.9 | B, CyTOF®, FA, FC, WB | Low Endotoxin |
| CD11c In Vivo Antibody | Human | 3.9 | B, CyTOF®, FA, FC, IHC FF, WB | Ultra Low Endotoxin |
| CD155 (PVR) In Vivo Antibody | Mouse | 4.24.1 | FC | Low Endotoxin |
| CD155 (PVR) In Vivo Antibody | Mouse | 4.24.1 | FC | Ultra Low Endotoxin |
| CD44 [IM7] In Vivo Antibody | Human, Mouse | IM7 | CODEX®, CyTOF®, ELISA Det, FC, ICC, IHC FF, IHC FFPE, IP, WB | Low Endotoxin |
| CD44 [IM7] In Vivo Antibody | Baboon, Chimpanzee, Rhesus, Bovine, Horse, Human, Mouse, Pig | IM7 | CODEX®, CyTOF®, ELISA Det, FC, ICC, IHC FF, IHC FFPE, IP, WB | Ultra Low Endotoxin |
| ICAM-1 (CD54) [BE29G1] In Vivo Antibody | Mouse | BE29G1 | B, IP, WB | Ultra Low Endotoxin |
| ICAM-1 (CD54) [BE29G1] In Vivo Antibody | Mouse | BE29G1 | B, IP, WB | Low Endotoxin |
| Integrin β7 In Vivo Antibody | Human/Mouse | FIB504 | B, CyTOF®, FC, IP | Low Endotoxin |
| LPAM-1 In Vivo Antibody | Mouse | DATK32 | B, FC, IHC FF, IP | Low Endotoxin |
| LPAM-1 In Vivo Antibody | Mouse | DATK32 | B, FC, IHC FF, IP | Ultra Low Endotoxin |
| CD62L In Vivo Antibody | Human | DREG56 | B, CODEX®, FC, IF, IHC FF, WB | Low Endotoxin |
| CD62L In Vivo Antibody | Human | DREG56 | B, CODEX®, FC, IF, IHC FF, WB | Ultra Low Endotoxin |
| TGF-β1, 2, 3 In Vivo Antibody | Bovine, Hamster, Human, Mouse, Rat | 1D11.16.8 | IHC, N, WB | Low Endotoxin |
| TGF-β1, 2, 3 In Vivo Antibody | Human, Mouse | 1D11.16.8 | IHC, N, WB | Ultra Low Endotoxin |
T セル (T-Cells)
T-Cell 欠落
CD4+ T-Cell 欠落
CD8+ T-Cell 欠落
| Product Name | Reactivity | Clone | Application | Endotoxin Level |
|---|---|---|---|---|
| CD8a (Ly 2) In Vivo Antibody | Mouse | 53-6.7 | B, CODEX®, CyTOF®, Depletion, FC, IHC FF, IP, WB | Low Endotoxin |
| CD8a (Ly 2) In Vivo Antibody | Mouse | 53-6.7 | B, CODEX®, CyTOF®, Depletion, FC, IHC FF, IP, WB | Ultra Low Endotoxin |
| CD8a (Ly 2.2) In Vivo Antibody | Mouse | 2.43 | Depletion, FA, FC, ICC, IF Staining, IHC FFPE, IP | Low Endotoxin |
| CD8a (Ly 2.2) In Vivo Antibody | Mouse | 2.43 | Depletion, FA, FC, ICC, IF Staining, IHC FFPE, IP | Ultra Low Endotoxin |
| CD8b.2 In Vivo Antibody | Mouse | 53-5.8 | Depletion, FA, FC, ICC, WB | Low Endotoxin |
| CD8b.2 In Vivo Antibody | Mouse | 53-5.8 | Depletion, FA, FC, ICC, WB | Ultra Low Endotoxin |
| CD8 In Vivo Antibody | Mouse | YTS-169 | Depletion, FC, IHC FF, WB | Low Endotoxin |
| CD8 [YTS 169] In Vivo Antibody | Mouse | YTS-169 | Depletion, FC, IHC FF, WB | Ultra Low Endotoxin |
T-Reg Cell 欠落
| Product Name | Reactivity | Clone | Application | Endotoxin Level |
|---|---|---|---|---|
| CD25 In Vivo Antibody | Mouse | PC61 | B, CODEX®, Depletion, FA, FC, IHC FF, IP, WB | Low Endotoxin |
| CD25 In Vivo Antibody | Mouse | PC61 | B, CODEX®, Depletion, FA, FC, IHC FF, IP, WB | Ultra Low Endotoxin |
γδ T-Cell 欠落
| Product Name | Reactivity | Clone | Application | Endotoxin Level |
|---|---|---|---|---|
| TCR V gamma 2 In Vivo Antibody | Mouse | UC3-10A6 | Depletion, FC, IP | Low Endotoxin |
| Vγ2 TCR In Vivo Antibody | Mouse | UC3-10A6 | Depletion, FC, IP | Ultra Low Endotoxin |
B セル (B-Cells)
B セルの枯渇
| Product Name | Reactivity | Clone | Application | Endotoxin Level |
|---|---|---|---|---|
| CD45R [RA3-6B2] In Vivo Antibody | Mouse/Human | RA3-6B2 | Act, CODEX®, CyTOF®, Depletion, FA, FC, IHC FF, IP | Ultra Low Endotoxin |
| CD45R [RA3-6B2] In Vivo Antibody | Mouse/Human | RA3-6B2 | Act, CODEX®, CyTOF®, Depletion, FA, FC, IHC FF, IP | Low Endotoxin |
| CD19 In Vivo Antibody | Mouse | 1D3 | B, CODEX®, Depletion, FC, IHC FF, IP, WB | Low Endotoxin |
| CD19 In Vivo Antibody | Mouse | 1D3 | B, CODEX®, Depletion, FC, IHC FF, IP, WB | Ultra Low Endotoxin |
その他の免疫細胞
先天性リンパ細胞枯渇nbsp;
NK細胞枯渇
マクロファージ細胞枯渇
好中球細胞枯渇
サイトカイン、ケモカインおよび受容体
サイトカイン、ケモカインおよび受容体
インターフェロン
| Product Name | Reactivity | Clone | Application | Endotoxin Level |
|---|---|---|---|---|
| IFNγ [XMG1.2] In Vivo Antibody | Mouse | XMG1.2 | CyTOF®, ELISA Cap, ELISPOT, ICFC, IHC FF, N, WB | Low Endotoxin |
| IFNγ [H22] In Vivo Antibody | Mouse | H22 | IP, N, WB | Low Endotoxin |
| IFNγ [H22] In Vivo Antibody | Mouse | H22 | ELISA, IF, IP, N, WB | Ultra Low Endotoxin |
| IFNß In Vivo Antibody | Mouse | HDß-4A7 | B, FA, N, WB | Low Endotoxin |
| IFNß In Vivo Antibody | Mouse | HDß-4A7 | B, FA, N, WB | Ultra Low Endotoxin |
| IFNα In Vivo Antibody | Mouse | TIF-3C5 | B, FA, N, WB | Low Endotoxin |
| IFNα In Vivo Antibody | Mouse | TIF-3C5 | B, FA, N, WB | Ultra Low Endotoxin |
| IFNβ In Vivo Antibody | Mouse | MIB-5E9.1 | N, WB | Low Endotoxin |
| IFNAR-1 In Vivo Antibody | Mouse | MAR1-5A3 | B,ELISA,FC,IP,WB | Low Endotoxin |
MHCおよびその他の抗体
| Product Name | Reactivity | Clone | Application | Endotoxin Level |
|---|---|---|---|---|
| H-2b In Vivo Antibody | Mouse | B8-24-3 | FA | Low Endotoxin |
| H-2Kb (MHC Class I) [Y-3] In Vivo Antibody | Mouse | Y-3 | FA, ICC, IP, WB | Low Endotoxin |
| H-2Kb (MHC Class I) [Y-3] In Vivo Antibody | Mouse | Y-3 | FA, ICC, IP, WB | Ultra Low Endotoxin |
| H-2Kd (MHC Class I) In Vivo Antibody | Mouse | A4C8.1-Do9 | FC, WB | Low Endotoxin |
| CD32/CD16 In Vivo Antibody | Mouse | 2.4G2 | B, CODEX®, FA, FC, IHC FF, IP, WB | Low Endotoxin |
| CD32/CD16 In Vivo Antibody | Mouse | 2.4G2 | CODEX®, FC, IHC FF, IP, WB | Ultra Low Endotoxin |
| CD3ε [500A2] In Vivo Antibody | Mouse | 500A2 | B, FC, IHC FF | Low Endotoxin |
| CD3ε [500A2] In Vivo Antibody | Mouse | 500A2 | B, FC, IHC FF | Ultra Low Endotoxin |
| Dendritic Cells In Vivo Antibody | Mouse | 33D1 | WB | Low Endotoxin |
| Dendritic Cells In Vivo Antibody | Mouse | 33D1 | WB | Ultra Low Endotoxin |
| Ly-6C [7B10] In Vivo Antibody | Mouse | 7B10 | WB | Low Endotoxin |
| Ly-6C [HK1.4] In Vivo Antibody | Mouse | HK1.4 | CODEX®, CyTOF®, IHC FF, IP, WB | Low Endotoxin |
ヒト、非ヒト霊長類およびその他の種
すべての抗体;
| Product Name | Reactivity | Clone | Application | Endotoxin Level |
|---|---|---|---|---|
| Alpha Defensin-5 [8C8] In Vivo Antibody | Human | 8C8 | Dot, ELISA, IHC FFPE, WB | Low Endotoxin |
| HLA-A, B, C (MHC Class I) In Vivo Antibody | Baboon, Chimpanzee, Cynomolgus Monkey, Feline, Bovine, Human | W6/32 | B, CODEX®, FC, IHC FF, IP, WB | Low Endotoxin |
| HLA-A, B, C (MHC Class I) In Vivo Antibody | Baboon, Chimpanzee, Cynomolgus Monkey, Feline, Bovine, Human | W6/32 | B, CODEX®, FC, IHC FF, IP, WB | Ultra Low Endotoxin |
| CD71 In Vivo Antibody | Human | T56/14 | FC, WB | Low Endotoxin |
| CD71 In Vivo Antibody | Human | T56/14 | FC, IHC | Ultra Low Endotoxin |
| CD20 In Vivo Antibody | Human | 2H7 | CyTOF®, FC, WB | Low Endotoxin |
| CD20 In Vivo Antibody | Human | 2H7 | CyTOF®, FC, WB | Ultra Low Endotoxin |
| HLA-DR (MHC Class II) In Vivo Antibody | Baboon, Chimpanzee, Cynomolgus Monkey, Marmoset, Rhesus Monkey, Squirrel Monkey, Canine, Human | L243 | B, CODEX®, CyTOF®, FC, IHC FF, IP, WB | Low Endotoxin |
| HLA-DR (MHC Class II) In Vivo Antibody | Baboon, Chimpanzee, Cynomolgus Monkey, Marmoset, Rhesus Monkey, Squirrel Monkey, Canine, Human | L243 | B, CODEX®, CyTOF®, Depletion, FC, IHC FF, IP, WB | Ultra Low Endotoxin |
| CD44 [IM7] In Vivo Antibody | Human, Mouse | IM7 | CODEX®, CyTOF®, ELISA Det, FC, ICC, IHC FF, IHC FFPE, IP, WB | Low Endotoxin |
| CD44 [IM7] In Vivo Antibody | Baboon, Chimpanzee, Rhesus, Bovine, Horse, Human, Mouse, Pig | IM7 | CODEX®, CyTOF®, ELISA Det, FC, ICC, IHC FF, IHC FFPE, IP, WB | Ultra Low Endotoxin |
| TGF-β1, 2, 3 In Vivo Antibody | Bovine, Hamster, Human, Mouse, Rat | 1D11.16.8 | IHC, N, WB | Low Endotoxin |
| TGF-β1, 2, 3 In Vivo Antibody | Human, Mouse | 1D11.16.8 | IHC, N, WB | Ultra Low Endotoxin |
| Alpha Defensin-5 [8C8] In Vivo Antibody | Human | 8C8 | Dot, ELISA, IHC FFPE, WB | Low Endotoxin |
| CD119 (IFN-γ Rα Chain) In Vivo Antibody | Human | GIR-208 | FA, FC | Low Endotoxin |
| CD119 (IFN-γ Rα Chain) In Vivo Antibody | Human | GIR-208 | FA, FC | Ultra Low Endotoxin |
| CD11a In Vivo Antibody | Human | 38 | Costim, FC, WB | Low Endotoxin |
| CD11a In Vivo Antibody | Human | 38 | Costim, FC, WB | Ultra Low Endotoxin |
| CD11b In Vivo Antibody | Human | ICRF44 | CODEX®, FC, IF Staining, IHC FF | Low Endotoxin |
| CD11b In Vivo Antibody | Human | ICRF44 | CODEX®, FC, IF Staining, IHC FF | Ultra Low Endotoxin |
| CD11c In Vivo Antibody | Human | 3.9 | B, CyTOF®, FA, FC, WB | Low Endotoxin |
| CD11c In Vivo Antibody | Human | 3.9 | B, CyTOF®, FA, FC, IHC FF, WB | Ultra Low Endotoxin |
| CD14 In Vivo Antibody | Human | UCHM-1 | FC, WB | Low Endotoxin |
| CD16 [3G8] In Vivo Antibody | Baboon, Chimpanzee, Cynomolgus Monkey, Marmoset, Pigtailed Macaque, Rhesus Monkey, Squirrel Monkey, Human | 3G8 | B, CyTOF®, FC, IHC FF, IP | Low Endotoxin |
| CD16 [3G8] In Vivo Antibody | Baboon, Chimpanzee, Cynomolgus Monkey, Marmoset, Pigtailed Macaque, Rhesus Monkey, Squirrel Monkey, Human | 3G8 | B, CyTOF®, FC, IHC FF, IP | Ultra Low Endotoxin |
| CD2 In Vivo Antibody | Human | G11 | Costim, FC, IHC, WB | Low Endotoxin |
| PD-L2 (CD273) In Vivo Antibody | Mouse/Human | 3.2.B8 | B, FC, WB | Ultra Low Endotoxin |
| PD-L2 (CD273) In Vivo Antibody | Mouse/Human | 3.2.B8 | B, FC | Low Endotoxin |
| CD3 [UCHT-1] In Vivo Antibody | Human | UCHT-1 | Act, CODEX®, CyTOF®, FC, IF Staining, IHC FF, IP, WB | Low Endotoxin |
| CD3 In Vivo Antibody | Human | UCHT-1 | CODEX®, CyTOF®, FC, IF Staining, IHC FF, IP, WB | Ultra Low Endotoxin |
| CD38 [OKT10] In Vivo Antibody | Rhesus Monkey, Human | OKT10 | FC | Low Endotoxin |
| CD38 [OKT10] In Vivo Antibody | Rhesus Monkey, Human | OKT10 | FC | Ultra Low Endotoxin |
| CD62L In Vivo Antibody | Human | DREG56 | B, CODEX®, FC, IF, IHC FF, WB | Low Endotoxin |
| CD62L In Vivo Antibody | Human | DREG56 | B, CODEX®, FC, IF, IHC FF, WB | Ultra Low Endotoxin |
| CD7 In Vivo Antibody | Human | T3-3A1 | FC, IF Staining | Low Endotoxin |
| CD8 In Vivo Antibody | Human | UCHT-4 | FA, FC, WB | Low Endotoxin |
| CD8 In Vivo Antibody | Human | UCHT-4 | FA, FC, WB | Ultra Low Endotoxin |
| EGFR In Vivo Antibody | Human | EGFR.1 | IHC, WB | Low Endotoxin |
| EGFR In Vivo Antibody | Human | EGFR.1 | WB | Ultra Low Endotoxin |
| Fibulin-4 [5G11] In Vivo Antibody | Human | 5G11 | IF Microscopy, IF Staining, IHC FFPE, WB | Low Endotoxin |
| Hepsin [3H10.1] In Vivo Antibody | Human | 3H10.1 | ELISA, FC | Low Endotoxin |
| HLA A2,B7 (MHC Class I) In Vivo Antibody | Human | BB7.6 | FC | Low Endotoxin |
| HLA-DP (MHC Class II) Monomorphic In Vivo Antibody | Human | B7/21 | FC, ICC | Low Endotoxin |
| HLA-DQ (MHC Class II) In Vivo Antibody | Human | 1a3 | ELISA, FC, IP, WB | Low Endotoxin |
| HLA-DQ (MHC Class II) In Vivo Antibody | Human | 1a3 | ELISA, FC, IP, WB | Ultra Low Endotoxin |
| ICAM-1 In Vivo Antibody | Human | 15.2 | FC, IHC FFPE, IP, WB | Low Endotoxin |
| ICAM-1 In Vivo Antibody | Human | 15.2 | FC, IHC FFPE, IP, WB | Ultra Low Endotoxin |
| TCR Vα24-Jα18 (iNKT cell) In Vivo Antibody | Human | 6B11 | CyTOF®, FC | Low Endotoxin |
| TCR Vα24-Jα18 (iNKT cell) In Vivo Antibody | Human | 6B11 | CyTOF®, FC | Ultra Low Endotoxin |
| CD318 In Vivo Antibody | Human/Mouse | 9A2 | FC | Low Endotoxin |
| CD45R [RA3-6B2] In Vivo Antibody | Mouse/Human | RA3-6B2 | Act, CODEX®, CyTOF®, Depletion, FA, FC, IHC FF, IP | Ultra Low Endotoxin |
| CD45R [RA3-6B2] In Vivo Antibody | Mouse/Human | RA3-6B2 | Act, CODEX®, CyTOF®, Depletion, FA, FC, IHC FF, IP | Low Endotoxin |
| TGF-β1, 2, 3 In Vivo Antibody | Bovine, Hamster, Human, Mouse, Rat | 1D11.16.8 | IHC, N, WB | Low Endotoxin |
| TGF-β1, 2, 3 In Vivo Antibody | Human, Mouse | 1D11.16.8 | IHC, N, WB | Ultra Low Endotoxin |
| IL-1β In Vivo Antibody | Mouse | B122 | IP, N, WB | Low Endotoxin |
| IL-4 In Vivo Antibody | Mouse | 11B11 | CyTOF®, ELISA Cap, ELISPOT, FA, ICC, IHC, IP, N | Low Endotoxin |
等式制御
| Product Name | Reactivity | Clone | Application | Endotoxin Level |
|---|---|---|---|---|
| IgG Isotype Control | PIP | FC | Low Endotoxin | |
| IgG Isotype Control | PIP | FC | Ultra Low Endotoxin | |
| IgG1 Isotype Control [HKSP] | HKSP | Low Endotoxin | ||
| IgG1 Isotype Control [HKSP84] | HKSP84 | Low Endotoxin | ||
| IgG1 Isotype Control [HKSP84] | HKSP84 | Ultra Low Endotoxin | ||
| IgG1 Isotype Control [HKSP] | HKSP | Ultra Low Endotoxin | ||
| IgG2a Isotype Control | C1.18.4 | Low Endotoxin | ||
| IgG2a Isotype Control | C1.18.4 | Ultra Low Endotoxin | ||
| IgG2b Isotype Control | MPC-11 | Low Endotoxin | ||
| IgG2b Isotype Control | MPC-11 | Ultra Low Endotoxin | ||
| IgG3 Isotype Control | MG3-35 | Low Endotoxin | ||
| IgG3 Isotype Control | MG3-35 | Ultra Low Endotoxin | ||
| IgM Isotype Control | Low Endotoxin | |||
| IgM Isotype Control | Ultra Low Endotoxin | |||
| IgG1 Isotype Control | GL113 | Low Endotoxin | ||
| IgG1 Isotype Control | GL113 | Ultra Low Endotoxin | ||
| IgG2a Isotype Control | 1-1 | Ultra Low Endotoxin | ||
| IgG2a Isotype Control | 1-1 | Low Endotoxin | ||
| IgG2b Isotype Control | 1-2 | Low Endotoxin | ||
| IgG2b Isotype Control | 1-2 | Ultra Low Endotoxin |
バイオシミラー抗体
フルレンジ
| Product Name | Clone | Reactivity | Application |
| Anti-Adalimumab (TNF alpha) Antibody | AFS98 | Human | B, ELISA, FA, FC, IF, IHC, IP, N |
| Anti-Mogamulizumab (CD194 / CCR4) Antibody | AFS98 | Human | Depletion, ELISA, FA, FC |
| Anti-Mogamulizumab (CD194 / CCR4) Antibody (Fc Reduced) | MP4-25D2 | Human | Depletion, ELISA, FA, FC |
| Anti-Adalimumab (TNF alpha) Antibody (Fc Reduced) | MAR1-5A3 | Human | B, ELISA, FA, FC, IF, IHC, IP, N |
| Anti-Natalizumab (CD49D / Integrin alpha 4) Antibody | ALF-161 | Human | B, FC |
| Anti-Natalizumab (CD49D / Integrin alpha 4) Antibody (Fc Reduced) | JAMA-147 | Human | B, FC |
| Anti-Nivolumab (CD279 / PD-1) Antibody | TN3-19.12 | Human/Cynomolgus Monkey | B, FA, FC, IHC |
| Anti-Nivolumab (CD279 / PD-1) Antibody (Fc Reduced) | TN3-19.12 | Human/Cynomolgus Monkey | B, FA, FC, IHC |
| Anti-Oxelumab (OX40L) Antibody | Y-3 | Human | B, FA, FC |
| Anti-Oxelumab (OX40L) Antibody (Fc Reduced) | Y-3 | Human | B, FA, FC |
| Anti-Tabalumab (CD257 / BAFF) Antibody | 7G7B6 | Human/Cynomolgus Monkey/Rabbit | ELISA, FA, FC, IF, IP, N, WB |
| Anti-Tabalumab (CD257 / BAFF) Antibody (Fc Reduced) | OKT-4 | Human/Cynomolgus Monkey/Rabbit | ELISA, FA, FC, IF, IP, N, WB |
| Anti-Trastuzumab (HER-2) Antibody | G28.5 | Human | CyTOF, ELISA, FC, IHC |
| Anti-Trastuzumab (HER-2) Antibody (Fc Reduced) | W6/32 | Human | CyTOF, ELISA, FC, IHC |
| Anti-Ipilimumab (CTLA-4) Antibody | W6/32 | Human | B, CyTOF, ELISA, FC |
| Anti-Ipilimumab (CTLA-4) Antibody (Fc Reduced) | T56/14 | Human | B, CyTOF, ELISA, FC |
| Anti-Sarilumab (IL-6) Antibody | T56/14 | Human | B, ELISA, FA, FC, IHC, N, WB |
| Anti-Sarilumab (IL-6) Antibody (Fc Reduced) | 2H7 | Human | B, ELISA, FA, FC, IHC, N, WB |
| Anti-SARS-CoV-2 Spike RBD [2165] | 2H7 | SARS-CoV-2 ⋅ Virus | ELISA, IHC, N |
| Anti-SARS-CoV-2 Spike RBD [2165] - Biotin | L243 | SARS-CoV-2 ⋅ Virus | ELISA, IHC |
| Anti-SARS-CoV-2 Spike RBD [2165] - HRP | L243 | SARS-CoV-2 ⋅ Virus | ELISA, IHC |
| Anti-Alemtuzumab (CD52) Antibody | XMG1.2 | Human/Rhesus Monkey/Cynomolgus Monkey | CyTOF, ELISA, FA, FC, IHC FF, IHC FFPE, WB |
| Anti-SARS-CoV-2 Spike NTD [2146] | C17.8 | SARS-CoV-2 ⋅ Virus | ELISA, IHC |
| Anti-SARS-CoV-2 Spike NTD [2146] - Biotin | JES6-1A12 | SARS-CoV-2 ⋅ Virus | ELISA, IHC |
| Anti-SARS-CoV-2 Spike NTD [2146] - HRP | 1A8 | SARS-CoV-2 ⋅ Virus | ELISA, IHC |
| Anti-Alemtuzumab (CD52) Antibody (Fc Reduced) | 1A8 | Human/Rhesus Monkey/Cynomolgus Monkey | CyTOF, ELISA, FA, FC, IHC FF, IHC FFPE, WB |
| Anti-Basiliximab (IL-2R alpha / CD25) Antibody | 2.4G2 | Human/Rhesus Monkey/Cynomolgus Monkey | B, CyTOF, FC, IF, IHC, WB |
| Anti-SARS-CoV-2 Spike RBD [2838] | 2.4G2 | SARS-CoV-2 ⋅ Virus | ELISA |
| Anti-Basiliximab (IL-2R alpha / CD25) Antibody (Fc Reduced) | P84 | Human/Rhesus Monkey/Cynomolgus Monkey | B, CyTOF, FC, IF, IHC, WB |
| Anti-Bevacizumab (VEGF) Antibody | P84 | Human | B, ELISA, FC, IP, N, WB |
| Anti-SARS-CoV-2 Spike RBD [2381] | 29F.1A12 | SARS-CoV-2 ⋅ Virus | ELISA |
| Anti-Bevacizumab (VEGF) Antibody (Fc Reduced) | 29F.1A12 | Human | B, ELISA, FC, IP, N, WB |
| Anti-Briakinumab (IL 12/23) Antibody | H22 | Human | B, ELISA, FA, FC, IF, IP, N, WB |
| Anti-SARS-CoV-2 Spike RBD [2355] | H22 | SARS-CoV-2 ⋅ Virus | ELISA, N |
| Anti-Briakinumab (IL 12/23) Antibody (Fc Reduced) | UC7-13D5 | Human | B, ELISA, FA, FC, IF, IP, N, WB |
| Anti-Cetuximab (EGFR) Antibody | UC7-13D5 | Human | B, CyTOF, ELISA, FC, ICC, IHC |
| Anti-SARS-CoV-2 Spike NTD [2215] | RMP1-14 | SARS-CoV-2 ⋅ Virus | ELISA |
| Anti-Cetuximab (EGFR) Antibody (Fc Reduced) | RMP1-14 | Human | B, CyTOF, FC |
| Anti-SARS-CoV-2 Nucleocapsid (N) | TY25 | SARS-CoV-2 ⋅ Virus | ELISA, IHC, WB |
| Anti-Rituximab (CD20) Antibody | FD441.8 | Human/Rhesus Monkey/Cynomolgus Monkey | FC |
| Anti-Rituximab (CD20) Antibody (Fc Reduced) | FD441.8 | Human/Rhesus Monkey/Cynomolgus Monkey | FC |
| Anti-Human NRG1-β1 - Biotin | M1/70 | Human | ELISA Det, WB |
低vs超低生体抗体品質基準
生物分析データ
Figure 1. Quality control for different lots of PD-1 [RMP1-14] antibody. All the in vivo antibodies undergo extensive quality control ensuring extreme lot-to-lot reproducibility. Endotoxin data for eight lots demonstrate that all lots were below the specification of ≤ 0.5 EU/mg as determined by the limulus amebocyte lysate (LAL) method (Fig. 1A). Analysis by size exclusion chromatography visualized by superimposing chromatograms for all nine lots, with overlapping retention times and minimal baseline noise (Fig. 1B). All lots show high purity as shown by non-reducing and reducing SDS-PAGE (Fig. 1C and 1D).
精製された生体内超低グレード抗体のためのIDEXXIMPACT I（PCRベース）マウス病原体プロファイル
有効性と許容性のベンチマーク
Independent comparison of the in vivo efficacy and tolerability of clones of mAbs anti-PD-1 [RMP1-14 and 29F.1A12], anti-PD-L1 [10F.9G2], and anti-CTLA-4 [9H10] and isotype controls versus Vendor B using a CT26 syngeneic model (murine colorectal carcinoma derived from BALB/c mice). All antibodies had matching isotype controls (Table 2), and phosphate-buffered saline (PBS) was used as a control.
一般的なin vivo抗体
| PD-1 [RMP1-14] In Vivo Antibody Ultra-Low Endotoxin | |
|---|---|
| Reactivity | Mouse |
| Clone | RMP1-14 |
| Application | B, FA, WB |
| PD-L1 [B7-H1] In Vivo Antibody Ultra-Low Endotoxin | |
|---|---|
| Reactivity | Mouse |
| Clone | 10F.9G2 |
| Application | B, CODEX®, FA, IHC FF, WB |
| CTLA-4 [9H10] In Vivo Antibody Ultra-Low Endotoxin | |
|---|---|
| Reactivity | Mouse |
| Clone | 9H10 |
| Application | B, WB |
| CD28 In Vivo Antibody Ultra-Low Endotoxin | |
|---|---|
| Reactivity | Mouse |
| Clone | 37.51 |
| Application | B, Costim, CyTOF®, FA, IP, WB |
| TGF-β1, 2, 3 In Vivo Antibody Ultra-Low Endotoxin | |
|---|---|
| Reactivity | Human/ Mouse |
| Clone | 1D11.16.8 |
| Application | IHC, N, WB |
| GM-CSF In Vivo Antibody Ultra-Low Endotoxin | |
|---|---|
| Reactivity | Mouse |
| Clone | MP1-22E9 |
| Application | N, WB |
| TNFα In Vivo Antibody Ultra-Low Endotoxin | |
|---|---|
| Reactivity | Mouse |
| Clone | TN3-19.12 |
| Application | IP, N, WB |
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研究のための関連ツール
臨床研究をサポートするために、我々は抗体、ELISAキット、多重パネルなどのいくつかの重要な生物学的研究ツールを開発し、他の様々なバイオマーカーとともに多数の炎症マーカーを測定しました。
22nd Jun 2023
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