Anti-Transferrin Antibody (CAB19130)
- SKU:
- CAB19130
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-Transferrin Antibody |
| 抗体コード: | CAB19130 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human Transferrin |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: | Human serum |
| 免疫原: | A synthesized peptide derived from human Transferrin |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 7018 |
| Uniprot: | P02787 |
| セルラーロケーション: | |
| 計算された分子量: | 77kDa |
| 観察された分子量: | 77kDa |
 | Western blot - Transferrin Rabbit mAb (CAB19130) |
| 同義語: | HEL-S-71p, PRO1557, PRO2086, TFQTL1, TF, Transferrin |
| バックグラウンド: | This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009] |
| UniProt Protein Function: | TF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Defects in TF are the cause of atransferrinemia (ATRAF). Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Belongs to the transferrin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 3q22.1 Cellular Component: extracellular space; cell surface; early endosome; cytoplasmic membrane-bound vesicle; extracellular region; coated pit; recycling endosome; perinuclear region of cytoplasm; endocytic vesicle; apical plasma membrane; late endosome; basal plasma membrane; endosome membrane; vesicle Molecular Function:protein binding; ferric iron binding; ubiquitin protein ligase binding Biological Process: platelet activation; retinal homeostasis; platelet degranulation; cellular iron ion homeostasis; transferrin transport; blood coagulation; transmembrane transport Disease: Atransferrinemia |
| NCBI Summary: | This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009] |
| UniProt Code: | P02787 |
| NCBI GenInfo Identifier: | 313104271 |
| NCBI Gene ID: | 7018 |
| NCBI Accession: | P02787.3 |
| UniProt Secondary Accession: | P02787,O43890, Q1HBA5, Q9NQB8, Q9UHV0, |
| UniProt Related Accession: | P02787 |
| Molecular Weight: | 77,064 Da |
| NCBI Full Name: | Serotransferrin |
| NCBI Synonym Full Names: | transferrin |
| NCBI Official Symbol: | TF |
| NCBI Official Synonym Symbols: | TFQTL1; PRO1557; PRO2086 |
| NCBI Protein Information: | serotransferrin; siderophilin; beta-1 metal-binding globulin |
| UniProt Protein Name: | Serotransferrin |
| UniProt Synonym Protein Names: | Beta-1 metal-binding globulin; Siderophilin |
| Protein Family: | Transferrin |
| UniProt Gene Name: | TF |
| UniProt Entry Name: | TRFE_HUMAN |