Anti-TACO1 Antibody (CAB15445)
- SKU:
- CAB15445
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-TACO1 Antibody |
| 抗体コード: | CAB15445 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-297 of human TACO1 (NP_057444.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-251MG, LO2, A375, Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Rat lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-297 of human TACO1 (NP_057444.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSAW AAAS LSRA AARC LLAR GPGV RAAP PRDP RPSH PEPR GCGA APGR TLHF TAAV PAGH NKWS KVRH IKGP KDVE RSRI FSKL CLNI RLAV KEGG PNPE HNSN LANI LEVC RSKH MPKS TIET ALKM EKSK DTYL LYEG RGPG GSSL LIEA LSNS SHKC QADI RHIL NKNG GVMA VGAR HSFD KKGV IVVE VEDR EKKA VNLE RALE MAIE AGAE DVKE TEDE EERN VFKF ICDA SSLH QVRK KLDS LGLC SVSC ALEF IPNS KVQL AEPD LEQA AHLI QALS NHED VIHV YDNI E |
| 遺伝子ID: | 51204 |
| Uniprot: | Q9BSH4 |
| セルラーロケーション: | Mitochondrion |
| 計算された分子量: | 32kDa |
| 観察された分子量: | 32kDa |
| 同義語: | TACO1, CCDC44 |
| バックグラウンド: | This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome. |
| UniProt Protein Function: | CCDC44: Acts as a translational activator of mitochondrially- encoded cytochrome c oxidase 1. Defects in TACO1 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency. Belongs to the TACO1 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 17q23.3 Cellular Component: mitochondrion; nucleus Disease: Mitochondrial Complex Iv Deficiency |
| NCBI Summary: | This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.[provided by RefSeq, Mar 2010] |
| UniProt Code: | Q9BSH4 |
| NCBI GenInfo Identifier: | 33516968 |
| NCBI Gene ID: | 51204 |
| NCBI Accession: | Q9BSH4.1 |
| UniProt Secondary Accession: | Q9BSH4,Q8N3N6, Q9UI60, B2RD21, |
| UniProt Related Accession: | Q9BSH4 |
| Molecular Weight: | 32,477 Da |
| NCBI Full Name: | Translational activator of cytochrome c oxidase 1 |
| NCBI Synonym Full Names: | translational activator of cytochrome c oxidase I |
| NCBI Official Symbol: | TACO1 |
| NCBI Official Synonym Symbols: | CCDC44 |
| NCBI Protein Information: | translational activator of cytochrome c oxidase 1 |
| UniProt Protein Name: | Translational activator of cytochrome c oxidase 1 |
| UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 44; Translational activator of mitochondrially-encoded cytochrome c oxidase I |
| Protein Family: | Translational activator of cytochrome c oxidase |
| UniProt Gene Name: | TACO1 |
| UniProt Entry Name: | TACO1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TACO1 antibody (CAB15445) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded Human colon carcinoma using TACO1 Rabbit pAb (CAB15445) at dilution of 1:100 (40x lens). |
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