| UniProt Protein Function: | Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells. |
| UniProt Code: | Q92536 |
| NCBI GenInfo Identifier: | 115648022 |
| NCBI Gene ID: | 9057 |
| NCBI Accession: | NP_003974.3 |
| UniProt Secondary Accession: | Q92536,Q68DS4, Q7L1N3, |
| UniProt Related Accession: | Q92536 |
| Molecular Weight: | 56.8kDa |
| NCBI Full Name: | Y+L amino acid transporter 2 |
| NCBI Synonym Full Names: | solute carrier family 7 member 6 |
| NCBI Official Symbol: | SLC7A6 |
| NCBI Official Synonym Symbols: | LAT3; LAT-2; y+LAT-2 |
| NCBI Protein Information: | Y+L amino acid transporter 2 |
| UniProt Protein Name: | Y+L amino acid transporter 2 |
| UniProt Synonym Protein Names: | Cationic amino acid transporter, y+ system; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2 |
| UniProt Gene Name: | SLC7A6 |
