Anti-SLC6A14 Antibody (CAB10582)
- SKU:
- CAB10582
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-SLC6A14 Antibody |
| 抗体コード: | CAB10582 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 131-234 of human SLC6A14 (NP_009162.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | A-549, MCF7, SGC-7901 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 131-234 of human SLC6A14 (NP_009162.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | YYNV IIAY SLYY MFAS FQSE LPWK NCSS WSDK NCSR SPIV THCN VSTV NKGI QEII QMNK SWVD INNF TCIN GSEI YQPG QLPS EQYW NKVA LQRS SGMN ETGV |
| 遺伝子ID: | 11254 |
| Uniprot: | Q9UN76 |
| セルラーロケーション: | Membrane, Multi-pass membrane protein |
| 計算された分子量: | 72kDa |
| 観察された分子量: | 72kDa |
| 同義語: | SLC6A14, BMIQ11 |
| バックグラウンド: | This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X. |
| UniProt Protein Function: | SLC6A14: Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner. Genetic variations in SLC6A14 may be associated with obesity in some populations, as shown by significant differences in allele frequencies between obese and non-obese individuals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A14 subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: Xq23 Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane; vesicle Molecular Function:amino acid transmembrane transporter activity; transporter activity Biological Process: amino acid metabolic process; amino acid transport; response to toxin; transport Disease: Body Mass Index Quantitative Trait Locus 11 |
| NCBI Summary: | This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, May 2010] |
| UniProt Code: | Q9UN76 |
| NCBI GenInfo Identifier: | 41018156 |
| NCBI Gene ID: | 11254 |
| NCBI Accession: | Q9UN76.1 |
| UniProt Secondary Accession: | Q9UN76,Q5H942, |
| UniProt Related Accession: | Q9UN76 |
| Molecular Weight: | 72kDa |
| NCBI Full Name: | Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) |
| NCBI Synonym Full Names: | solute carrier family 6 member 14 |
| NCBI Official Symbol: | SLC6A14 |
| NCBI Official Synonym Symbols: | BMIQ11 |
| NCBI Protein Information: | sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) |
| UniProt Protein Name: | Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) |
| UniProt Synonym Protein Names: | Amino acid transporter ATB0+; Solute carrier family 6 member 14 |
| Protein Family: | Sodium- and chloride-dependent neutral and basic amino acid transporter |
| UniProt Gene Name: | SLC6A14 |
 | Western blot analysis of extracts of various cell lines, using SLC6A14 antibody (CAB10582) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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