Anti-SLC39A7 Antibody (CAB3343)
- SKU:
- CAB3343
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-SLC39A7 Antibody |
| 抗体コード: | CAB3343 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 235-380 of human SLC39A7 (NP_008910.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:1000 - 1:3000 IHC 1:100 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, A-431, LO2, HeLa, Mouse heart, Mouse pancreas, Mouse liver, Rat heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 235-380 of human SLC39A7 (NP_008910.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | KFVR HVKG GHGH SHGH GHAH SHTR GSHG HGRQ ERST KEKQ SSEE EEKE TRGV QKRR GGST VPKD GPVR PQNA EEEK RGLD LRVS GYLN LAAD LAHN FTDG LAIG ASFR GGRG LGIL TTMT VLLH EVPH EVGD FAIL VQSG CSKK QA |
| 遺伝子ID: | 7922 |
| Uniprot: | Q92504 |
| セルラーロケーション: | Endoplasmic reticulum membrane, Golgi apparatus, Multi-pass membrane protein, cis-Golgi network membrane |
| 計算された分子量: | 50kDa |
| 観察された分子量: | 50kDa |
| 同義語: | SLC39A7, D6S115E, D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7 |
| バックグラウンド: | The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | SLC39A7: transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011] |
| UniProt Protein Details: | Protein type:Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: nucleoplasm; Golgi apparatus; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane Molecular Function:metal ion transmembrane transporter activity; protein binding Biological Process: zinc ion transport; transmembrane transport |
| NCBI Summary: | The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| UniProt Code: | Q92504 |
| NCBI GenInfo Identifier: | 12643344 |
| NCBI Gene ID: | 7922 |
| NCBI Accession: | Q92504.2 |
| UniProt Secondary Accession: | Q92504,Q5STP8, Q9UIQ0, B0UXF6, |
| UniProt Related Accession: | Q92504 |
| Molecular Weight: | 469 |
| NCBI Full Name: | Zinc transporter SLC39A7 |
| NCBI Synonym Full Names: | solute carrier family 39 (zinc transporter), member 7 |
| NCBI Official Symbol: | SLC39A7 |
| NCBI Official Synonym Symbols: | KE4; HKE4; ZIP7; RING5; H2-KE4; D6S115E; D6S2244E |
| NCBI Protein Information: | zinc transporter SLC39A7; zrt-, Irt-like protein 7; Ke4 gene, mouse, human homolog of; solute carrier family 39 member 7; histidine-rich membrane protein Ke4; really interesting new gene 5 protein; HLA class II region expressed gene KE4 |
| UniProt Protein Name: | Zinc transporter SLC39A7 |
| UniProt Synonym Protein Names: | Histidine-rich membrane protein Ke4; Really interesting new gene 5 protein; Solute carrier family 39 member 7; Zrt-, Irt-like protein 7; ZIP7 |
| Protein Family: | Zinc transporter |
| UniProt Gene Name: | SLC39A7 |
| UniProt Entry Name: | S39A7_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLC39A7 antibody (CAB3343) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 20s. |
 | Immunohistochemistry of paraffin-embedded rat testis using SLC39A7 antibody (CAB3343) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat kidney using SLC39A7 antibody (CAB3343) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human liver using SLC39A7 antibody (CAB3343) at dilution of 1:100 (40x lens). |
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