Anti-SLC25A26 Antibody (CAB15557)
- SKU:
- CAB15557
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-SLC25A26 Antibody |
| 抗体コード: | CAB15557 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 105-185 of human SLC25A26 (NP_775742.4). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse testis, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 105-185 of human SLC25A26 (NP_775742.4). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | IRVP SEVV KQRA QVSA STRT FQIF SNIL YEEG IQGL YRGY KSTV LREI PFSL VQFP LWES LKAL WSWR QDHV VDSW QSAV C |
| 遺伝子ID: | 115286 |
| Uniprot: | Q70HW3 |
| セルラーロケーション: | Mitochondrion inner membrane, Multi-pass membrane protein |
| 計算された分子量: | 7kDa/20kDa/29kDa |
| 観察された分子量: | 33kDa |
| 同義語: | SLC25A26, COXPD28, SAMC |
| バックグラウンド: | This gene is a member of the mitochondrial carrier family which includes nuclear-encoded transporters localized on the inner mitochondrial membranes. Members of the family transport important small molecules across the mitochondrial inner membrane. This protein is involved in the transport of S-adenosylmethionine (SAM) into the mitochondria. Mutations in this gene are associated with combined oxidative phosphorylation deficiency 28. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | SLC25A26: Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Specifically mediates the transport of S- adenosylmethionine (SAM) into the mitochondria. Belongs to the mitochondrial carrier family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family; Mitochondrial Chromosomal Location of Human Ortholog: 3p14.1 Cellular Component: integral to membrane; mitochondrial inner membrane; mitochondrion Molecular Function:S-adenosylmethionine transmembrane transporter activity; structural constituent of ribosome Biological Process: S-adenosylmethionine transport; translation |
| NCBI Summary: | Mitochondrial carriers, including SLC25A26, are a family of transport proteins found mostly in the inner membranes of mitochondria. They shuttle metabolites and cofactors through the mitochondrial membrane (Agrimi et al., 2004 [PubMed 14674884]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q70HW3 |
| NCBI GenInfo Identifier: | 258645122 |
| NCBI Gene ID: | 115286 |
| NCBI Accession: | NP_001158268.1 |
| UniProt Secondary Accession: | Q70HW3,Q7Z786, Q96E68, A8K758, B3KRZ7, |
| UniProt Related Accession: | Q70HW3 |
| Molecular Weight: | 7,405 Da |
| NCBI Full Name: | S-adenosylmethionine mitochondrial carrier protein isoform b |
| NCBI Synonym Full Names: | solute carrier family 25 (S-adenosylmethionine carrier), member 26 |
| NCBI Official Symbol: | SLC25A26 |
| NCBI Official Synonym Symbols: | SAMC |
| NCBI Protein Information: | S-adenosylmethionine mitochondrial carrier protein |
| UniProt Protein Name: | S-adenosylmethionine mitochondrial carrier protein |
| UniProt Synonym Protein Names: | Mitochondrial S-adenosylmethionine transporter; Solute carrier family 25 member 26 |
| Protein Family: | S-adenosylmethionine mitochondrial carrier protein |
| UniProt Gene Name: | SLC25A26 |
| UniProt Entry Name: | SAMC_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLC25A26 antibody (CAB15557) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90S. |
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