Anti-SLC25A14 Antibody (CAB13731)
- SKU:
- CAB13731
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-SLC25A14 Antibody |
| 抗体コード: | CAB13731 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-200 of human SLC25A14 (NP_001269124.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-200 of human SLC25A14 (NP_001269124.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GHQK STTV SHEM SGLN WKPF VYGG LASI VAEF GTFP VDLT KTRL QVQG QSID ARFK EIKY RGMF HALF RICK EEGV LALY SGIA PALL RQAS YGTI KIGI YQSL KRLF VERL EDET LLIN MICG VVSG VISS TIAN PTDV LKIR MQAQ GSLF QGSM IGSF IDIY QQEG TRGL WRGV |
| 遺伝子ID: | 9016 |
| Uniprot: | O95258 |
| セルラーロケーション: | Mitochondrion inner membrane, Multi-pass membrane protein |
| 計算された分子量: | 35kDa/36kDa/39kDa |
| 観察された分子量: | 36kDa |
| 同義語: | SLC25A14, BMCP1, UCP5 |
| バックグラウンド: | Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4. |
| UniProt Protein Function: | SLC25A14: Participates in the mitochondrial proton leak measured in brain mitochondria. Belongs to the mitochondrial carrier family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Mitochondrial; Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral; Transporter Chromosomal Location of Human Ortholog: Xq24 Cellular Component: mitochondrion; integral to plasma membrane; mitochondrial inner membrane Biological Process: transport; aerobic respiration; mitochondrial transport |
| NCBI Summary: | Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2013] |
| UniProt Code: | O95258 |
| NCBI GenInfo Identifier: | 37181304 |
| NCBI Gene ID: | 9016 |
| NCBI Accession: | AAQ88466.1 |
| UniProt Secondary Accession: | O95258,Q0VDH7, Q9HC60, Q9HC61, D3DTG2, |
| UniProt Related Accession: | O95258 |
| Molecular Weight: | 39,173 Da |
| NCBI Full Name: | UCP5 |
| NCBI Synonym Full Names: | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
| NCBI Official Symbol: | SLC25A14 |
| NCBI Official Synonym Symbols: | UCP5; BMCP1 |
| NCBI Protein Information: | brain mitochondrial carrier protein 1 |
| UniProt Protein Name: | Brain mitochondrial carrier protein 1 |
| UniProt Synonym Protein Names: | Mitochondrial uncoupling protein 5; UCP 5; Solute carrier family 25 member 14 |
| UniProt Gene Name: | SLC25A14 |
| UniProt Entry Name: | UCP5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLC25A14 antibody (CAB13731) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (RM00020)._Exposure time: 90s. |
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