Anti-MARCH7 Antibody (CAB16308)
- SKU:
- CAB16308
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-MARCH7 Antibody |
| 抗体コード: | CAB16308 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 425-704 of human MARCH7 (NP_073737.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 425-704 of human MARCH7 (NP_073737.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RRES NEVV HLEA QNDP LGAA ANRP QASA ASSS ATTG GSTS DSAQ GGRN TGIS GILP GSLF RFAV PPAL GSNL TDNV MITV DIIP SGWN SADG KSDK TKSA PSRD PERL QKIK ESLL LEDS EEEE GDLC RICQ MAAA SSSN LLIE PCKC TGSL QYVH QDCM KKWL QAKI NSGS SLEA VTTC ELCK EKLE LNLE DFDI HELH RAHA NEQA EYEF ISSG LYLV VLLH LCEQ SFSD MMGN TNEP STRV RFIN LART LQAH MEDL ETSE DDSE EDGD HNRT FDIA |
| 遺伝子ID: | 64844 |
| Uniprot: | Q9H992 |
| セルラーロケーション: | |
| 計算された分子量: | 73kDa/78kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | MARCH7, AXO, AXOT, MARCH-VII, RNF177 |
| バックグラウンド: | MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]). |
| UniProt Protein Function: | MARCH7: E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.19; Ligase; EC 6.3.2.- Chromosomal Location of Human Ortholog: 2q24.2 |
| NCBI Summary: | MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010] |
| UniProt Code: | Q9H992 |
| NCBI GenInfo Identifier: | 74762745 |
| NCBI Gene ID: | 64844 |
| NCBI Accession: | Q9H992.1 |
| UniProt Secondary Accession: | Q9H992,Q53GQ1, Q9BTR9, A8K9X1, B7Z7P5, D3DPB0, |
| UniProt Related Accession: | Q9H992 |
| Molecular Weight: | 73,778 Da |
| NCBI Full Name: | E3 ubiquitin-protein ligase MARCH7 |
| NCBI Synonym Full Names: | membrane associated ring-CH-type finger 7 |
| NCBI Official Symbol: | MARCH7 |
| NCBI Official Synonym Symbols: | AXO; AXOT; RNF177; MARCH-VII |
| NCBI Protein Information: | E3 ubiquitin-protein ligase MARCH7 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase MARCH7 |
| UniProt Synonym Protein Names: | Axotrophin; Membrane-associated RING finger protein 7; Membrane-associated RING-CH protein VII; MARCH-VII; RING finger protein 177 |
| UniProt Gene Name: | MARCH7 |
| UniProt Entry Name: | MARH7_HUMAN |
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