Anti-KCTD10 Antibody (CAB12115)
- SKU:
- CAB12115
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-KCTD10 Antibody |
| 抗体コード: | CAB12115 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human KCTD10 (NP_114160.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human KCTD10 (NP_114160.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MEEM SGES VVSS AVPA AATR TTSF KGTS PSSK YVKL NVGG ALYY TTMQ TLTK QDTM LKAM FSGR MEVL TDSE GWIL IDRC GKHF GTIL NYLR DGAV PLPE SRRE IEEL LAEA KYYL VQGL VEEC QAAL QNKD TYEP FCKV PVIT SSKE EQKL IATS NKPA |
| 遺伝子ID: | 83892 |
| Uniprot: | Q9H3F6 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 17kDa/32kDa/35kDa |
| 観察された分子量: | 35kDa |
| 同義語: | KCTD10, BTBD28, MSTP028, ULRO61, hBACURD3 |
| バックグラウンド: | The protein encoded by this gene binds proliferating cell nuclear antigen (PCNA) and may be involved in DNA synthesis and cell proliferation. In addition, the encoded protein may be a tumor suppressor. Several protein-coding and non-protein coding transcript variants have been found for this gene. |
| UniProt Protein Function: | KCTD10: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome. Belongs to the BACURD family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 12q24.11 Cellular Component: nucleoplasm; cytoplasm Molecular Function:ubiquitin-protein ligase activity Biological Process: proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; protein homooligomerization |
| UniProt Code: | Q9H3F6 |
| NCBI GenInfo Identifier: | 74733570 |
| NCBI Gene ID: | 83892 |
| NCBI Accession: | Q9H3F6.1 |
| UniProt Secondary Accession: | Q9H3F6,Q53HN2, Q59FV1, Q6PL47, Q96SU0, |
| UniProt Related Accession: | Q9H3F6 |
| Molecular Weight: | 17,985 Da |
| NCBI Full Name: | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 |
| NCBI Synonym Full Names: | potassium channel tetramerization domain containing 10 |
| NCBI Official Symbol: | KCTD10 |
| NCBI Official Synonym Symbols: | BTBD28; ULRO61; MSTP028; hBACURD3 |
| NCBI Protein Information: | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3; BTB/POZ domain-containing protein KCTD10; potassium channel tetramerisation domain containing 10; potassium channel tetramerization domain-containing protein 10 |
| UniProt Protein Name: | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 |
| UniProt Synonym Protein Names: | BTB/POZ domain-containing protein KCTD10; Potassium channel tetramerization domain-containing protein 10 |
| Protein Family: | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein |
| UniProt Gene Name: | KCTD10 |
| UniProt Entry Name: | BACD3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using KCTD10 Antibody (CAB12115) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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