Anti-KCNS3 Antibody (CAB7906)
- SKU:
- CAB7906
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-KCNS3 Antibody |
| 抗体コード: | CAB7906 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human KCNS3 (NP_002243.3). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, SGC-7901, HT-29, Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human KCNS3 (NP_002243.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MVFG EFFH RPGQ DEEL VNLN VGGF KQSV DQST LLRF PHTR LGKL LTCH SEEA ILEL CDDY SVAD KEYY FDRN PSLF RYVL NFYY TGKL HVME ELCV FSFC QEIE YWGI NELF IDSC CSNR YQER KEEN HEKD WDQK SHDV STDS SFEE SSLF EKEL EKFD TLRF GQLR KKIW IRME NPAY |
| 遺伝子ID: | 3790 |
| Uniprot: | Q9BQ31 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 56kDa |
| 観察された分子量: | 56kDa |
| 同義語: | KCNS3, KV9.3 |
| バックグラウンド: | Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| UniProt Protein Function: | Kv9.3: Potassium channel subunit. Modulates channel activity and reduces the ion flow. Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 2p24 Cellular Component: cytoplasm; Golgi apparatus; integral to membrane; plasma membrane Molecular Function:delayed rectifier potassium channel activity; potassium channel regulator activity Biological Process: potassium ion transport; regulation of insulin secretion |
| NCBI Summary: | Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013] |
| UniProt Code: | Q9BQ31 |
| NCBI GenInfo Identifier: | 311033434 |
| NCBI Gene ID: | 3790 |
| NCBI Accession: | Q9BQ31.3 |
| UniProt Secondary Accession: | Q9BQ31,O43651, Q4ZFY1, Q96B56, D6W520, |
| UniProt Related Accession: | Q9BQ31 |
| Molecular Weight: | 56,001 Da |
| NCBI Full Name: | Potassium voltage-gated channel subfamily S member 3 |
| NCBI Synonym Full Names: | potassium voltage-gated channel modifier subfamily S member 3 |
| NCBI Official Symbol: | KCNS3 |
| NCBI Official Synonym Symbols: | KV9.3 |
| NCBI Protein Information: | potassium voltage-gated channel subfamily S member 3 |
| UniProt Protein Name: | Potassium voltage-gated channel subfamily S member 3 |
| UniProt Synonym Protein Names: | Delayed-rectifier K(+) channel alpha subunit 3; Voltage-gated potassium channel subunit Kv9.3 |
| Protein Family: | Potassium voltage-gated channel subfamily |
| UniProt Gene Name: | KCNS3 |
| UniProt Entry Name: | KCNS3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using KCNS3 antibody (CAB7906) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat ovary using KCNS3 antibody (CAB7906) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human colon carcinoma using KCNS3 antibody (CAB7906) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse spleen using KCNS3 antibody (CAB7906) at dilution of 1:100 (40x lens). |
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