Anti-HBG1 Antibody (CAB0704)
- SKU:
- CAB0704
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HBG-T2
- Synonyms:
- HBGA
- Synonyms:
- HBGR
- Synonyms:
- HSGGL1
- Synonyms:
- PRO2979
Frequently bought together:
Description
抗体名: | HBG1 Rabbit mAb |
抗体コード: | CAB0704 |
サイズ: | 20uL, 50uL, 100uL |
同義語: | HBG-T2, HBGA, HBGR, HSGGL1, PRO2979 |
申し込み: | WB, IHC, IF |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human HBG1 |
申し込み: | WB, IHC, IF |
推奨される希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | Mouse kidney |
免疫原: | A synthesized peptide derived from human HBG1 |
精製方法: | Affinity purification |
保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 3047/3048 |
Uniprot: | P69891/P69892_ |
計算された分子量: | 12kDa |
観察された分子量: | 12KDa |
UniProt Protein Function: | HBG1: Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Belongs to the globin family. |
UniProt Protein Details: | Protein type:Carrier Chromosomal Location of Human Ortholog: 11p15.5 Cellular Component: cytosol Biological Process: blood coagulation Disease: Fetal Hemoglobin Quantitative Trait Locus 1 |
NCBI Summary: | The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008] |
UniProt Code: | P69891 |
NCBI GenInfo Identifier: | 56749860 |
NCBI Gene ID: | 3047 |
NCBI Accession: | P69891.2 |
UniProt Secondary Accession: | P69891,P02096, P62027, Q549G1, Q8TDA1, Q96FH7, |
UniProt Related Accession: | P69891 |
Molecular Weight: | 16,140 Da |
NCBI Full Name: | Hemoglobin subunit gamma-1 |
NCBI Synonym Full Names: | hemoglobin subunit gamma 1 |
NCBI Official Symbol: | HBG1 |
NCBI Official Synonym Symbols: | HBGA; HBGR; HBG-T2; HSGGL1; PRO2979 |
NCBI Protein Information: | hemoglobin subunit gamma-1 |
UniProt Protein Name: | Hemoglobin subunit gamma-1 |
UniProt Synonym Protein Names: | Gamma-1-globin; Hb F Agamma; Hemoglobin gamma-1 chain; Hemoglobin gamma-A chain |
Protein Family: | Hemoglobin |
UniProt Gene Name: | HBG1 |
UniProt Entry Name: | HBG1_HUMAN |