Anti-GABRG1 Antibody (CAB14240)
- SKU:
- CAB14240
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-GABRG1 Antibody |
| 抗体コード: | CAB14240 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-260 of human GABRG1 (NP_775807.2). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-260 of human GABRG1 (NP_775807.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | HSCP LEFS SYGY PKNE IEYK WKKP SVEV ADPK YWRL YQFA FVGL RNST EITH TISG DYVI M |
| 遺伝子ID: | 2565 |
| Uniprot: | Q8N1C3 |
| セルラーロケーション: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse |
| 計算された分子量: | 53kDa |
| 観察された分子量: | 54kDa |
| 同義語: | GABRG1 |
| バックグラウンド: | The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. This gene is clustered with three other family members on chromosome 4. |
| UniProt Protein Function: | GABRG1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG1 sub-subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 4p12 Molecular Function:GABA-A receptor activity |
| NCBI Summary: | The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. This gene is clustered with three other family members on chromosome 4. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8N1C3 |
| NCBI GenInfo Identifier: | 209572630 |
| NCBI Gene ID: | 2565 |
| NCBI Accession: | Q8N1C3.2 |
| UniProt Secondary Accession: | Q8N1C3,Q5H9T8, |
| UniProt Related Accession: | Q8N1C3 |
| Molecular Weight: | 53,595 Da |
| NCBI Full Name: | Gamma-aminobutyric acid receptor subunit gamma-1 |
| NCBI Synonym Full Names: | gamma-aminobutyric acid type A receptor gamma1 subunit |
| NCBI Official Symbol: | GABRG1 |
| NCBI Protein Information: | gamma-aminobutyric acid receptor subunit gamma-1 |
| UniProt Protein Name: | Gamma-aminobutyric acid receptor subunit gamma-1 |
| UniProt Synonym Protein Names: | GABA(A) receptor subunit gamma-1 |
| Protein Family: | Gamma-aminobutyric acid receptor |
| UniProt Gene Name: | GABRG1 |
| UniProt Entry Name: | GBRG1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GABRG1 antibody (CAB14240) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Immunofluorescence analysis of C6 cells using GABRG1 Rabbit pAb (CAB14240) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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