Anti-FABP5 Antibody (CAB6373)
- SKU:
- CAB6373
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-FABP5 Antibody |
| 抗体コード: | CAB6373 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human FABP5 (NP_001435.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse skin, Mouse thymus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human FABP5 (NP_001435.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MATV QQLE GRWR LVDS KGFD EYMK ELGV GIAL RKMG AMAK PDCI ITCD GKNL TIKT ESTL KTTQ FSCT LGEK FEET TADG RKTQ TVCN FTDG ALVQ HQEW DGKE STIT RKLK DGKL VVEC VMNN VTCT RIYE KVE |
| 遺伝子ID: | 2171 |
| Uniprot: | Q01469 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 15kDa |
| 観察された分子量: | 12kDa |
| 同義語: | FABP5, E-FABP, EFABP, KFABP, PA-FABP, PAFABP |
| バックグラウンド: | This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. |
| UniProt Protein Function: | FABP5: High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
| UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 8q21.13 Cellular Component: nucleoplasm; cytoplasm; cytosol Molecular Function:protein binding; transporter activity; fatty acid binding; lipid binding Biological Process: epidermis development; phosphatidylcholine biosynthetic process; glucose metabolic process; lipid metabolic process; glucose transport |
| NCBI Summary: | This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011] |
| UniProt Code: | Q01469 |
| NCBI GenInfo Identifier: | 232081 |
| NCBI Gene ID: | 2171 |
| NCBI Accession: | Q01469.3 |
| UniProt Secondary Accession: | Q01469,B2R4K0, |
| UniProt Related Accession: | Q01469 |
| Molecular Weight: | 15,164 Da |
| NCBI Full Name: | Fatty acid-binding protein, epidermal |
| NCBI Synonym Full Names: | fatty acid binding protein 5 (psoriasis-associated) |
| NCBI Official Symbol: | FABP5 |
| NCBI Official Synonym Symbols: | EFABP; KFABP; E-FABP; PAFABP; PA-FABP |
| NCBI Protein Information: | fatty acid-binding protein, epidermal; epidermal-type fatty acid-binding protein; psoriasis-associated fatty acid-binding protein homolog |
| UniProt Protein Name: | Fatty acid-binding protein, epidermal |
| UniProt Synonym Protein Names: | Epidermal-type fatty acid-binding protein; E-FABP; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog |
| Protein Family: | Fatty acid-binding protein |
| UniProt Gene Name: | FABP5 |
| UniProt Entry Name: | FABP5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FABP5 antibody (CAB6373) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of A549 cells using FABP5 antibody (CAB6373). Blue: DAPI for nuclear staining. |
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