Anti-DCAF7 Antibody (CAB6787)
- SKU:
- CAB6787
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-DCAF7 Antibody |
| 抗体コード: | CAB6787 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human DCAF7 (NP_005819.3). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:10 - 1:100 |
| 反応性: | Human |
| ポジティブサンプル: | 293T |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human DCAF7 (NP_005819.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSLH GKRK EIYK YEAP WTVY AMNW SVRP DKRF RLAL GSFV EEYN NKVQ LVGL DEES SEFI CRNT FDHP YPTT KLMW IPDT KGVY PDLL ATSG DYLR VWRV GETE TRLE CLLN NNKN SDFC APLT SFDW NEVD PYLL GTSS IDTT CTIW GLET GQVL GRVN LVSG HVKT QLIA HDKE VYDI AFSR AGGG RDMF ASVG ADGS VRMF DLRH LEHS TIIY EDPQ HHPL LRLC WNKQ DPNY LATM AMDG MEVV ILDV RVPC TPVA RLNN HRAC VNGI AWAP HSSC HICT AADD HQAL IWDI QQMP RAIE DPIL AYTA EGEI NNVQ WAST QPDW IAIC YNNC LEIL RV |
| 遺伝子ID: | 10238 |
| Uniprot: | P61962 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 16kDa/38kDa |
| 観察された分子量: | 39kDa |
| 同義語: | DCAF7, AN11, HAN11, SWAN-1, WDR68 |
| バックグラウンド: | This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | WDR68: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 17q23.3 Cellular Component: cytoplasm; nuclear matrix; nucleoplasm; protein complex Molecular Function:protein binding Biological Process: protein ubiquitination |
| NCBI Summary: | This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| UniProt Code: | P61962 |
| NCBI GenInfo Identifier: | 48428729 |
| NCBI Gene ID: | 10238 |
| NCBI Accession: | P61962.1 |
| UniProt Secondary Accession: | P61962,O15491, Q9DAE4, B4E039, D3DU14, |
| UniProt Related Accession: | P61962 |
| Molecular Weight: | 16,340 Da |
| NCBI Full Name: | DDB1- and CUL4-associated factor 7 |
| NCBI Synonym Full Names: | DDB1 and CUL4 associated factor 7 |
| NCBI Official Symbol: | DCAF7 |
| NCBI Official Synonym Symbols: | AN11; HAN11; WDR68; SWAN-1 |
| NCBI Protein Information: | DDB1- and CUL4-associated factor 7 |
| UniProt Protein Name: | DDB1- and CUL4-associated factor 7 |
| UniProt Synonym Protein Names: | WD repeat-containing protein 68; WD repeat-containing protein An11 homolog |
| Protein Family: | DDB1- and CUL4-associated factor |
| UniProt Gene Name: | DCAF7 |
| UniProt Entry Name: | DCAF7_HUMAN |
 | Western blot analysis of extracts of 293T cells, using DCAF7 antibody (CAB6787) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of MCF7 cells using DCAF7 antibody (CAB6787). Blue: DAPI for nuclear staining. |
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