Anti-CGB Antibody (CAB1817)
- SKU:
- CAB1817
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-CGB Antibody |
| 抗体コード: | CAB1817 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human CGB |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: | MCF7, 293T, THP-1 |
| 免疫原: | Recombinant protein of human CGB |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 1082 |
| Uniprot: | P0DN86 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 18kDa |
| 観察された分子量: | 18kDa |
| 同義語: | CGB3, CGB, CGB5, CGB7, CGB8, hCGB |
| バックグラウンド: | This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. |
| UniProt Protein Function: | Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. |
| NCBI Summary: | This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P0DN86 |
| NCBI GenInfo Identifier: | 1027923599 |
| NCBI Gene ID: | 1082 |
| NCBI Accession: | P0DN86.1 |
| UniProt Related Accession: | P0DN86 |
| Molecular Weight: | |
| NCBI Full Name: | Choriogonadotropin subunit beta 3 |
| NCBI Synonym Full Names: | chorionic gonadotropin subunit beta 3 |
| NCBI Official Symbol: | CGB3 |
| NCBI Official Synonym Symbols: | CGB; CGB5; CGB7; CGB8; hCGB |
| NCBI Protein Information: | choriogonadotropin subunit beta 3 |
| UniProt Protein Name: | Choriogonadotropin subunit beta 3 |
| UniProt Synonym Protein Names: | Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotropin chain beta |
| UniProt Gene Name: | CGB3 |
 | Western blot analysis of extracts of various cell lines, using CGB Antibody (CAB1817) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 60s. |
 | Immunohistochemistry of paraffin-embedded human stomach using CGB antibody (CAB1817) at dilution of 1:100 (40x lens). |
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