Anti-CGB Antibody (CAB12419)

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SKU:
CAB12419
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-CGB Antibody
抗体コード:CAB12419
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 21-165 of human CGB (NP_000728.1).
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human, Mouse, Rat
ポジティブサンプル:MCF7
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 21-165 of human CGB (NP_000728.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:SKEP LRPR CRPI NATL AVEK EGCP VCIT VNTT ICAG YCPT MTRV LQGV LPAL PQVV CNYR DVRF ESIR LPGC PRGV NPVV SYAV ALSC QCAL CRRS TTDC GGPK DHPL TCDD PRFQ DSSS SKAP PPSL PSPS RLPG PSDT PILP Q
遺伝子ID:1082
Uniprot:P0DN86
セルラーロケーション:Secreted
計算された分子量:18kDa
観察された分子量:18kDa
同義語:CGB3, CGB, CGB5, CGB7, CGB8, hCGB
バックグラウンド:This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.
UniProt Protein Function:Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
NCBI Summary:This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]
UniProt Code:P0DN86
NCBI GenInfo Identifier:1027923599
NCBI Gene ID:1082
NCBI Accession:P0DN86.1
UniProt Related Accession:P0DN86
Molecular Weight:
NCBI Full Name:Choriogonadotropin subunit beta 3
NCBI Synonym Full Names:chorionic gonadotropin subunit beta 3
NCBI Official Symbol:CGB3  
NCBI Official Synonym Symbols:CGB; CGB5; CGB7; CGB8; hCGB  
NCBI Protein Information:choriogonadotropin subunit beta 3
UniProt Protein Name:Choriogonadotropin subunit beta 3
UniProt Synonym Protein Names:Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotropin chain beta
UniProt Gene Name:CGB3  
Anti-CGB Antibody (CAB12419)Western blot analysis of extracts of MCF7 cells, using CGB Rabbit pAb (CAB12419) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 10s.
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