Anti-CCT6B Antibody (CAB14615)
- SKU:
- CAB14615
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-CCT6B Antibody |
| 抗体コード: | CAB14615 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-340 of human CCT6B (NP_006575.2). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse testis, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-340 of human CCT6B (NP_006575.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AEGF EAAK IKAL EVLE EVKV TKEM KRKI LLDV ARTS LQTK VHAE LADV LTEV VVDS VLAV RRPG YPID LFMV EIME MKHK LGTD TKLI QGLV LDHG ARHP DMKK RVED AFIL ICNV SLEY EKTE VNSG FFYK TAEE KEKL VKAE RKFI EDRV QKII DLKD KVCA QSNK GFVV INQK GIDP FSLD SLAK HGIV ALRR AKRR NMER LSLA CGGM AVNS FEDL T |
| 遺伝子ID: | 10693 |
| Uniprot: | Q92526 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 53kDa/57kDa |
| 観察された分子量: | 58kDa |
| 同義語: | CCT6B, CCT-zeta-2, CCTZ-2, Cctz2, TCP-1-zeta-2, TSA303 |
| バックグラウンド: | This gene encodes a molecular chaperone that is a member of the chaperonin-containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | CCT-zeta-2: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. Belongs to the TCP-1 chaperonin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 17q12 Cellular Component: chaperonin-containing T-complex Molecular Function:unfolded protein binding; protein transporter activity; ATP binding Biological Process: protein transport; protein folding; spermatogenesis; chaperone-mediated protein complex assembly |
| NCBI Summary: | This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| UniProt Code: | Q92526 |
| NCBI GenInfo Identifier: | 119600607 |
| NCBI Gene ID: | 10693 |
| NCBI Accession: | EAW80201.1 |
| UniProt Secondary Accession: | Q92526,Q8TC34, B4DX20, B4DYB0, |
| UniProt Related Accession: | Q92526 |
| Molecular Weight: | 57,821 Da |
| NCBI Full Name: | chaperonin containing TCP1, subunit 6B (zeta 2) |
| NCBI Synonym Full Names: | chaperonin containing TCP1, subunit 6B (zeta 2) |
| NCBI Official Symbol: | CCT6B |
| NCBI Official Synonym Symbols: | Cctz2; CCTZ-2; TSA303; CCT-zeta-2; TCP-1-zeta-2 |
| NCBI Protein Information: | T-complex protein 1 subunit zeta-2; testis-specific Tcp20; testis-specific protein TSA303; T-complex protein 1, zeta-2 subunit |
| UniProt Protein Name: | T-complex protein 1 subunit zeta-2 |
| UniProt Synonym Protein Names: | CCT-zeta-2; CCT-zeta-like; TCP-1-zeta-like; Testis-specific Tcp20; Testis-specific protein TSA303 |
| Protein Family: | Choline-phosphate cytidylyltransferase |
| UniProt Gene Name: | CCT6B |
| UniProt Entry Name: | TCPW_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CCT6B antibody (CAB14615) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
 | Immunofluorescence analysis of HeLa cells using CCT6B antibody (CAB14615) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of L929 cells using CCT6B antibody (CAB14615) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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