Anti-ASB5 Antibody (CAB14449)
- SKU:
- CAB14449
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-ASB5 Antibody |
| 抗体コード: | CAB14449 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-329 of human ASB5 (NP_543150.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | 293T, A-431, HeLa, HepG2, Raji |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-329 of human ASB5 (NP_543150.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | NAIT IDGV TPLF NACS QGSP SCAE LLLE YGAK AQLE SCLP SPTH EAAS KGHH ECLD ILIS WGID VDQE IPHL GTPL YVAC MSQQ FHCI WKLL YAGA DVQK GKYW DTPL HAAA QQSS TEIV NLLL EFGA DINA KNTE LLRP IDVA TSSS MVER ILLQ HEAT PSSL YQLC RLCI RSYI GKPR LHLI PQLQ LPTL LKNF LQYR |
| 遺伝子ID: | 140458 |
| Uniprot: | Q8WWX0 |
| セルラーロケーション: | |
| 計算された分子量: | 30kDa/36kDa |
| 観察された分子量: | 36kDa |
| 同義語: | ASB5, ASB-5 |
| バックグラウンド: | The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. |
| UniProt Protein Function: | ASB5: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 4q34.2 Biological Process: protein ubiquitination |
| NCBI Summary: | The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8WWX0 |
| NCBI GenInfo Identifier: | 18254476 |
| NCBI Gene ID: | 140458 |
| NCBI Accession: | NP_543150.1 |
| UniProt Secondary Accession: | Q8WWX0,Q8N7B5, |
| UniProt Related Accession: | Q8WWX0 |
| Molecular Weight: | 30,083 Da |
| NCBI Full Name: | ankyrin repeat and SOCS box protein 5 |
| NCBI Synonym Full Names: | ankyrin repeat and SOCS box containing 5 |
| NCBI Official Symbol: | ASB5 |
| NCBI Official Synonym Symbols: | ASB-5 |
| NCBI Protein Information: | ankyrin repeat and SOCS box protein 5; SOCS box protein ASB-5; ankyrin repeat and SOCS box-containing 5 |
| UniProt Protein Name: | Ankyrin repeat and SOCS box protein 5 |
| Protein Family: | Ankyrin repeat and SOCS box protein |
| UniProt Gene Name: | ASB5 |
| UniProt Entry Name: | ASB5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ASB5 antibody (CAB14449) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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