Anti-ANO2 Antibody (CAB13109)
- SKU:
- CAB13109
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-ANO2 Antibody |
| 抗体コード: | CAB13109 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ANO2 (NP_001265526.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:1000 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ANO2 (NP_001265526.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MPED IPLL PGSP RRLS PQAG SRGG QGPK HGQQ CLKM PGPR APGL QGGS NRDP GQPC GGES TRSS SVIN NYLD ANEP VSLE ARLS RMHF HDSQ RKVD YVLA YHYR KRGV HLAQ GFPG HSLA IVSN GETG KEPH AGGP GDIE LGPL DALE EERK EQRE EFEH NLME AGLE LEKD LENK SQGS IFVR IHAP WQVL AREA EFLK |
| 遺伝子ID: | 57101 |
| Uniprot: | Q9NQ90 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 113kDa |
| 観察された分子量: | 114kDa |
| 同義語: | ANO2, C12orf3, TMEM16B |
| バックグラウンド: |
| UniProt Protein Function: | ANO2: Acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. May mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transporter, ion channel; Transporter; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 12p13.3 Cellular Component: nucleoplasm; nonmotile primary cilium; plasma membrane Molecular Function:protein homodimerization activity; intracellular calcium activated chloride channel activity; protein heterodimerization activity Biological Process: transmembrane transport |
| NCBI Summary: | ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011] |
| UniProt Code: | Q9NQ90 |
| NCBI GenInfo Identifier: | 262527528 |
| NCBI Gene ID: | 57101 |
| NCBI Accession: | Q9NQ90.2 |
| UniProt Secondary Accession: | Q9NQ90,Q9H847, C4N787, |
| UniProt Related Accession: | Q9NQ90 |
| Molecular Weight: | 1003 |
| NCBI Full Name: | Anoctamin-2 |
| NCBI Synonym Full Names: | anoctamin 2, calcium activated chloride channel |
| NCBI Official Symbol: | ANO2 |
| NCBI Official Synonym Symbols: | C12orf3; TMEM16B |
| NCBI Protein Information: | anoctamin-2; transmembrane protein 16B (eight membrane-spanning domains) |
| UniProt Protein Name: | Anoctamin-2 |
| UniProt Synonym Protein Names: | Transmembrane protein 16B |
| Protein Family: | Anoctamin |
| UniProt Gene Name: | ANO2 |
| UniProt Entry Name: | ANO2_HUMAN |
 | Western blot analysis of extracts of HeLa cells, using ANO2 antibody (CAB13109) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 20s. |
 | Immunohistochemistry of paraffin-embedded rat retina using ANO2 antibody (CAB13109) at dilution of 1:200 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse retina using ANO2 antibody (CAB13109) at dilution of 1:200 (40x lens). |
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