Anti-ADAP2 Antibody (CAB13738)

(No reviews yet) Write a Review
お見積り依頼
SKU:
CAB13738
Product type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
€0.00
Frequently bought together:

Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-ADAP2 Antibody
抗体コード:CAB13738
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Mouse
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human ADAP2 (NP_060874.1).
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Mouse
ポジティブサンプル:Mouse skeletal muscle
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human ADAP2 (NP_060874.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:MGDR ERNK KRLL ELLR APDT GNAH CADC GAAD PDWA SYKL GIFI CLNC CGVH RNFP DISR VKSV RLDF WDDS IVEF MIHN GNLR VKAK FEAR VPAF YYIP QAND CLVL KEQW IRAK YERR EFMA DGET ISLP GNRE GFLW KRGR DNSQ FLRR KFVL LARE GLLK YFTK EQGK SPKA VISI KDLN ATFQ TEKI GHPH GLQI TYRR DGHT RNLF VYHE SGKE IVDW FNAL RAAR LQYL KMAF PELP ESEL VPFL TRNY LKQG FMEK TGPK QKEP FKKR WFAL DCHE RRLL YYKN PLDA FEQG QVFL GNKE QGYE AYED LPKG IRGN RWKA GLTI VTPE RRFV LTCP SEKE QQEW LESL RGVL SSPL TPLN RLTA STES GRSS R
遺伝子ID:55803
Uniprot:Q9NPF8
セルラーロケーション:Cell membrane, Cytoplasm
計算された分子量:44kDa
観察された分子量:44kDa
同義語:ADAP2, CENTA2, HSA272195, cent-b
バックグラウンド:The protein encoded by this gene binds beta-tubulin and increases the stability of microtubules. The encoded protein can also translocate to the cell membrane and bind phosphatidylinositol 3, 4, 5-trisphosphate (PtdInsP3) and inositol 1, 3, 4, 5-tetrakisphosphate (InsP4). In addition, this protein is a GTPase-activating protein for ADP ribosylation factor 6 and may be able to block the entry of some RNA viruses.
UniProt Protein Function:CENTA2: GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Lipid-binding; Mitochondrial; GAPs; GAPs, ARF

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: mitochondrial envelope; cytoplasm; plasma membrane

Molecular Function:protein binding, bridging; phosphatidylinositol-4,5-bisphosphate binding; protein binding; phosphatidylinositol-3,4,5-triphosphate binding; inositol 1,3,4,5 tetrakisphosphate binding; zinc ion binding; phosphatidylinositol-3,4-bisphosphate binding

Biological Process: heart development; positive regulation of GTPase activity

UniProt Code:Q9NPF8
NCBI GenInfo Identifier:27923749
NCBI Gene ID:55803
NCBI Accession:Q9NPF8.1
UniProt Secondary Accession:Q9NPF8,Q8N4Q6, Q96SD5,
UniProt Related Accession:Q9NPF8
Molecular Weight:44,221 Da
NCBI Full Name:Arf-GAP with dual PH domain-containing protein 2
NCBI Synonym Full Names:ArfGAP with dual PH domains 2
NCBI Official Symbol:ADAP2  
NCBI Official Synonym Symbols:CENTA2; cent-b; HSA272195  
NCBI Protein Information:arf-GAP with dual PH domain-containing protein 2; centaurin beta; centaurin, alpha 2; centaurin-alpha 2 protein; centaurin-alpha-2; cnt-a2
UniProt Protein Name:Arf-GAP with dual PH domain-containing protein 2
UniProt Synonym Protein Names:Centaurin-alpha-2; Cnt-a2
Protein Family:Arf-GAP with dual PH domain-containing protein
UniProt Gene Name:ADAP2  
UniProt Entry Name:ADAP2_HUMAN
Anti-ADAP2 Antibody (CAB13738)Western blot analysis of extracts of mouse skeletal muscle, using ADAP2 antibody (CAB13738) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
View AllClose

View AllClose