| バックグラウンド: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
| NCBI Summary: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O15438 |
| NCBI GenInfo Identifier: | 15559191 |
| NCBI Gene ID: | 8714 |
| NCBI Accession: | CAC69553.1 |
| UniProt Related Accession: | O15438 |
| Molecular Weight: | 167,827 Da |
| NCBI Full Name: | multidrug resistance associated protein |
| NCBI Synonym Full Names: | ATP binding cassette subfamily C member 3 |
| NCBI Official Symbol: | ABCC3 |
| NCBI Official Synonym Symbols: | MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757 |
| NCBI Protein Information: | canalicular multispecific organic anion transporter 2 |
| UniProt Protein Name: | Multidrug resistance associated protein |
| UniProt Synonym Protein Names: | Multidrug resistance associated protein |
| Protein Family: | MIP-related peptides |
| UniProt Gene Name: | MRP3 |
