SLC9A9 Antibody (PACO06691)
- SKU:
- PACO06691
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 抗体名: | SLC9A9 Antibody (PACO06691) |
| 抗体コード: | PACO06691 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | ELISA:1:40000, WB:1:500-1:2000 |
| 反応性: | Human, Mouse |
| 免疫原: | Synthesized peptide derived from the Internal region of human NHE-9. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot analysis of Jurkat K562 NIH-3T3 cells using NHE-9 Polyclonal Antibody. |
 | Western Blot analysis of RAW264.7 cells using NHE-9 Polyclonal Antibody. |
| シノニム: | SLC9A9; NHE9; Nbla00118; Sodium/hydrogen exchanger 9; Na(+)/H(+) exchanger 9; NHE-9; Solute carrier family 9 member 9 |
| UniProt Protein Function: | NHE9: May act in electroneutral exchange of protons for Na(+) across membranes. Involved in the effusion of Golgi luminal H(+) in exchange for cytosolic cations. Involved in organelle ion homeostasis by contributing to the maintenance of the unique acidic pH values of the Golgi and post-Golgi compartments in the cell. A chromosomal aberration involving SLC9A9 has been found in a family with early-onset behavioral/developmental disorder with features of attention deficit-hyperactivity disorder and intellectual disability. Inversion inv(3)(p14:q21). The inversion disrupts DOCK3 and SLC9A9. Defects in SLC9A9 are a cause of susceptibility to autism type 16 (AUTS16). Autism is a complex multifactorial, pervasive developmental disorder characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Most individuals with autism also manifest moderate mental retardation. AUTS16 can be associated with epilepsy. Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. |
| UniProt Protein Details: | Protein type:Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q24 Cellular Component: recycling endosome; late endosome membrane; integral to membrane Molecular Function:protein binding; sodium:hydrogen antiporter activity Biological Process: regulation of pH; ion transport; transmembrane transport Disease: Autism, Susceptibility To, 16 |
| NCBI Summary: | This gene encodes a sodium/proton exchanger that is a member of the solute carrier 9 protein family. The encoded protein localizes the to the late recycling endosomes and may play an important role in maintaining cation homeostasis. Mutations in this gene are associated with autism susceptibility 16 and attention-deficit/hyperactivity disorder. [provided by RefSeq, Mar 2012] |
| UniProt Code: | Q8IVB4 |
| NCBI GenInfo Identifier: | 27734935 |
| NCBI Gene ID: | 285195 |
| NCBI Accession: | NP_775924.1 |
| UniProt Secondary Accession: | Q8IVB4,Q3LIC2, Q5JPI6, Q5WA58, Q8NAB9, A6NMQ9, |
| UniProt Related Accession: | Q8IVB4 |
| Molecular Weight: | 72,565 Da |
| NCBI Full Name: | sodium/hydrogen exchanger 9 |
| NCBI Synonym Full Names: | solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 |
| NCBI Official Symbol: | SLC9A9 |
| NCBI Official Synonym Symbols: | NHE9; AUTS16 |
| NCBI Protein Information: | sodium/hydrogen exchanger 9; Na(+)/H(+) exchanger 9; sodium/proton exchanger NHE9; putative protein product of Nbla00118; solute carrier family 9 (sodium/hydrogen exchanger), isoform 9 |
| UniProt Protein Name: | Sodium/hydrogen exchanger 9 |
| UniProt Synonym Protein Names: | Na(+)/H(+) exchanger 9; NHE-9; Solute carrier family 9 member 9 |
| Protein Family: | Sodium/hydrogen exchanger |
| UniProt Gene Name: | SLC9A9 |
| UniProt Entry Name: | SL9A9_HUMAN |