Anti-ZNRD1 Antibody (CAB13088)
- SKU:
- CAB13088
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-ZNRD1 Antibody |
| 抗体コード: | CAB13088 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-126 of human ZNRD1 (NP_055411.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | K-562, 293T |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-126 of human ZNRD1 (NP_055411.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSVM DLAN TCSS FQSD LDFC SDCG SVLP LPGA QDTV TCIR CGFN INVR DFEG KVVK TSVV FHQL GTAM PMSV EEGP ECQG PVVD RRCP RCGH EGMA YHTR QMRS ADEG QTVF YTCT NCKF QEKE DS |
| 遺伝子ID: | 30834 |
| Uniprot: | Q9P1U0 |
| セルラーロケーション: | Nucleus, nucleolus |
| 計算された分子量: | 13kDa |
| 観察された分子量: | 14kDa |
| 同義語: | ZNRD1, HTEX-6, HTEX6, Rpa12, TCTEX6, TEX6, ZR14, hZR14, tctex-6 |
| バックグラウンド: | This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | ZNRD1: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. |
| UniProt Protein Details: | Protein type:Transcription initiation complex; Transferase; Nucleolus Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: DNA-directed RNA polymerase I complex; nucleoplasm Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; positive regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter |
| NCBI Summary: | This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9P1U0 |
| NCBI GenInfo Identifier: | 71649339 |
| NCBI Gene ID: | 30834 |
| NCBI Accession: | Q9P1U0.1 |
| UniProt Secondary Accession: | Q9P1U0,Q1RMP0, Q5TM50, Q791N7, Q1XHV8, Q6MFY5, |
| UniProt Related Accession: | Q9P1U0 |
| Molecular Weight: | 13,904 Da |
| NCBI Full Name: | DNA-directed RNA polymerase I subunit RPA12 |
| NCBI Synonym Full Names: | zinc ribbon domain containing 1 |
| NCBI Official Symbol: | ZNRD1 |
| NCBI Official Synonym Symbols: | TEX6; ZR14; HTEX6; Rpa12; hZR14; HTEX-6; TCTEX6; tctex-6 |
| NCBI Protein Information: | DNA-directed RNA polymerase I subunit RPA12 |
| UniProt Protein Name: | DNA-directed RNA polymerase I subunit RPA12 |
| UniProt Synonym Protein Names: | Zinc ribbon domain-containing protein 1 |
| UniProt Gene Name: | ZNRD1 |
| UniProt Entry Name: | RPA12_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ZNRD1 antibody (CAB13088) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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