UniProt Protein Function: | Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr) (PubMed:27103431). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors (PubMed:27103431). |
NCBI Summary: | Summary: The protein encoded by this gene is a scaffolding subunit of the ATAC complex, which is a complex with acetyltransferase activity on histones H3 and H4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017] |
UniProt Code: | Q9ULM3 |
NCBI GenInfo Identifier: | 33620755 |
NCBI Gene ID: | 55689 |
NCBI Accession: | NP_060493.3 |
UniProt Secondary Accession: | Q9ULM3,Q641P6, Q9NW96, A7E2B9, D3DNS9, |
UniProt Related Accession: | Q9ULM3 |
Molecular Weight: | 150,782 Da |
NCBI Full Name: | YEATS domain-containing protein 2 isoform 3 |
NCBI Synonym Full Names: | YEATS domain containing 2 |
NCBI Official Symbol: | YEATS2 |
NCBI Protein Information: | YEATS domain-containing protein 2 |
UniProt Protein Name: | YEATS domain-containing protein 2 |
Protein Family: | YEATS domain-containing protein |
UniProt Gene Name: | YEATS2 |