Anti-YAP1 Antibody (CAB1002)[KO Validated]
![Anti-YAP1 Antibody (CAB1002)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/608x608/products/27724/27572/anti-yap1-antibody-cab1002ko-validated__51874__06910.1645806876.jpg?c=1 "Anti-YAP1 Antibody (CAB1002)[KO Validated]")
- SKU:
- CAB1002
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
![Anti-YAP1 Antibody (CAB1002)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/1280x1280/products/27724/27572/anti-yap1-antibody-cab1002ko-validated__51874__06910.1645806876.jpg?c=1&imbypass=on "Anti-YAP1 Antibody (CAB1002)[KO Validated]")
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Description
| 抗体名: | Anti-YAP1 Antibody [KO Validated] |
| 抗体コード: | CAB1002 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF IP |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1 (NP_001123617.1). |
| 申し込み: | WB IHC IF IP |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:20 - 1:50 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, LO2, BT-474, A549 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1 (NP_001123617.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PTAQ HLRQ SSFE IPDD VPLP AGWE MAKT SSGQ RYFL NHID QTTT WQDP RKAM LSQM NVTA PTSP PVQQ NMMN SASG PLPD GWEQ AMTQ DGEI YYIN HKNK TTSW LDPR LDPR FAMN QRIS QSAP VKQP PPLA PQSP QGGV MGGS NSNQ QQQM RLQQ LQME KERL RLKQ QELL RQAM RNIN PSTA NSPK CQEL ALRS QLPT LEQD GGTQ NPVS SPGM SQEL RTMT TNSS DPFL NSGT YHSR DEST DSGL SMSS YSVP RTPD DFLN SVDE MDTG DTIN QSTL PSQQ NRFP DYLE AIPG TNVD LGTL EGDG MNIE GEEL MPSL QEAL SSDI LNDM ESVL AATK LDKE SFLT WL |
| 遺伝子ID: | 10413 |
| Uniprot: | P46937 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa |
| 観察された分子量: | 72kDa |
| 同義語: | COB1, YAP, YAP2, YAP65, YKI, YAP1 |
| バックグラウンド: | This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Code: | P46937 |
| NCBI GenInfo Identifier: | 294862479 |
| NCBI Gene ID: | 10413 |
| NCBI Accession: | P46937.2 |
| UniProt Secondary Accession: | P46937,Q7Z574, B4DTY1, B7ZA01, E3WEB5, E3WEB6, E9PRV2 F5H202, K0KQ18, K0KYZ8, K0L195, K0L1G3, |
| UniProt Related Accession: | P46937 |
| Molecular Weight: | 504 |
| NCBI Full Name: | Transcriptional coactivator YAP1 |
| NCBI Synonym Full Names: | Yes-associated protein 1 |
| NCBI Official Symbol: | YAP1 |
| NCBI Official Synonym Symbols: | YAP; YKI; COB1; YAP2; YAP65 |
| NCBI Protein Information: | transcriptional coactivator YAP1; yorkie homolog; protein yorkie homolog; yes-associated protein 2; 65 kDa Yes-associated protein; yes-associated protein YAP65 homolog |
| UniProt Protein Name: | Transcriptional coactivator YAP1 |
| UniProt Synonym Protein Names: | Protein yorkie homolog; Yes-associated protein YAP65 homolog |
| Protein Family: | Transcriptional coactivator |
| UniProt Gene Name: | YAP1 |
| UniProt Entry Name: | YAP1_HUMAN |
![Anti-YAP1 Antibody [KO Validated] (CAB1002)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/t/673/A1002_1__85519.jpg) | Western blot analysis of extracts of various cell lines, using YAP1 antibody (CAB1002) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
![Anti-YAP1 Antibody [KO Validated] (CAB1002)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/d/795/A1002_2__81908.jpg) | Western blot analysis of extracts from normal (control) and [KO Validated] YAP1 Rabbit pAb knockout (KO) HeLa cells, using [KO Validated] YAP1 Rabbit pAb antibody (CAB1002) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
![Anti-YAP1 Antibody [KO Validated] (CAB1002)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/u/542/A1002_3__66609.jpg) | Immunohistochemistry of paraffin-embedded human placenta using YAP1 antibody (CAB1002) at dilution of 1:100 (40x lens). |
![Anti-YAP1 Antibody [KO Validated] (CAB1002)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/u/947/A1002_4__84089.jpg) | Immunohistochemistry of paraffin-embedded rat kidney using YAP1 antibody (CAB1002) at dilution of 1:100 (40x lens). |
![Anti-YAP1 Antibody [KO Validated] (CAB1002)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/b/202/A1002_5__00997.jpg) | Immunohistochemistry of paraffin-embedded mouse heart using YAP1 antibody (CAB1002) at dilution of 1:100 (40x lens). |
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