Anti-WBP2 Antibody (CAB16312)
- SKU:
- CAB16312
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-WBP2 Antibody |
| 抗体コード: | CAB16312 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 15-140 of human WBP2 (NP_036610.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, A-375, C6, Rat spleen |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 15-140 of human WBP2 (NP_036610.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VNNT ESIL MSYD HVEL TFND MKNV PEAF KGTK KGTV YLTP YRVI FLSK GKDA MQSF MMPF YLMK DCEI KQPV FGAN YIKG TVKA EAGG GWEG SASY KLTF TAGG AIEF GQRM LQVA SQAS RGEV PS |
| 遺伝子ID: | 23558 |
| Uniprot: | Q969T9 |
| セルラーロケーション: | |
| 計算された分子量: | 28kDa |
| 観察された分子量: | 28kDa |
| 同義語: | WBP2, GRAMD6, WBP-2 |
| バックグラウンド: | The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein that is a transcriptional coactivator of estrogen receptor alpha and progesterone receptor. Defects in this gene have been associated with hearing impairment. |
| UniProt Protein Function: | WBP2: Binds to the WW domain of YAP1, WWP1 and WWP2. Interacts with NEDD4. |
| UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Cell development/differentiation Chromosomal Location of Human Ortholog: 17q25 Cellular Component: nuclear chromatin Molecular Function:chromatin DNA binding; protein binding Biological Process: establishment of protein localization; positive regulation of gene expression, epigenetic; positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q969T9 |
| NCBI GenInfo Identifier: | 25091539 |
| NCBI Gene ID: | 23558 |
| NCBI Accession: | Q969T9.1 |
| UniProt Secondary Accession: | Q969T9,O95638, |
| UniProt Related Accession: | Q969T9 |
| Molecular Weight: | 28,087 Da |
| NCBI Full Name: | WW domain-binding protein 2 |
| NCBI Synonym Full Names: | WW domain binding protein 2 |
| NCBI Official Symbol: | WBP2 |
| NCBI Official Synonym Symbols: | WBP-2; GRAMD6 |
| NCBI Protein Information: | WW domain-binding protein 2 |
| UniProt Protein Name: | WW domain-binding protein 2 |
| Protein Family: | WW domain-binding protein |
| UniProt Gene Name: | WBP2 |
| UniProt Entry Name: | WBP2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using WBP2 antibody (CAB16312) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 120s. |
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