Anti-UCK2 Antibody (CAB10815)
- SKU:
- CAB10815
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-UCK2 Antibody |
| 抗体コード: | CAB10815 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human UCK2 (NP_036606.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | A-549, HeLa, 293T, B-cell, Mouse thymus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human UCK2 (NP_036606.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAGD SEQT LQNH QQPN GGEP FLIG VSGG TASG KSSV CAKI VQLL GQNE VDYR QKQV VILS QDSF YRVL TSEQ KAKA LKGQ FNFD HPDA FDNE LILK TLKE ITEG KTVQ IPVY DFVS HSRK EETV TVYP ADVV LFEG ILAF YSQE VRDL FQMK LFVD TDAD TRLS RRVL RDIS ERGR DLEQ ILSQ YITF VKPA FEEF CLPT KKYA DVII PRGA DNLV AINL IVQH IQDI LNGG PSKR QTNG CLNG YTPS RKRQ ASES SSRP H |
| 遺伝子ID: | 7371 |
| Uniprot: | Q9BZX2 |
| セルラーロケーション: | |
| 計算された分子量: | 12kDa/29kDa |
| 観察された分子量: | 29kDa |
| 同義語: | UCK2, TSA903, UK, UMPK |
| バックグラウンド: | This gene encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively. |
| UniProt Protein Function: | UCK2: Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4- thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)- benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5- methylcytidine, and N(4)-anisoylcytidine. Belongs to the uridine kinase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.7.1.48; Kinase, other; Nucleotide Metabolism - pyrimidine; Xenobiotic Metabolism - drug metabolism - other enzymes Chromosomal Location of Human Ortholog: 1q24.1 Cellular Component: cytosol Molecular Function:nucleoside kinase activity; uridine kinase activity Biological Process: pyrimidine base metabolic process; pyrimidine nucleoside salvage |
| NCBI Summary: | This gene encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively.[provided by RefSeq, Oct 2010] |
| UniProt Code: | Q9BZX2 |
| NCBI GenInfo Identifier: | 20455356 |
| NCBI Gene ID: | 7371 |
| NCBI Accession: | Q9BZX2.1 |
| UniProt Secondary Accession: | Q9BZX2,Q5VV91, Q7KZV3, Q92528, Q96KG5, Q9BU42, |
| UniProt Related Accession: | Q9BZX2 |
| Molecular Weight: | 29kDa |
| NCBI Full Name: | Uridine-cytidine kinase 2 |
| NCBI Synonym Full Names: | uridine-cytidine kinase 2 |
| NCBI Official Symbol: | UCK2 |
| NCBI Official Synonym Symbols: | UK; UMPK; TSA903 |
| NCBI Protein Information: | uridine-cytidine kinase 2 |
| UniProt Protein Name: | Uridine-cytidine kinase 2 |
| UniProt Synonym Protein Names: | Cytidine monophosphokinase 2; Testis-specific protein TSA903; Uridine monophosphokinase 2 |
| Protein Family: | Uridine-cytidine kinase |
| UniProt Gene Name: | UCK2 |
 | Western blot analysis of extracts of various cell lines, using UCK2 antibody (CAB10815) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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