Anti-TRMT61B Antibody (CAB8067)
- SKU:
- CAB8067
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | TRMT61B Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8067 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TRMT61B (NP_060380.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TRMT61B (NP_060380.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MLMA WCRG PVLL CLRQ GLGT NSFL HGLG QEPF EGAR SLCC RSSP RDLR DGER EHEA AQRK APGA ESCP SLPL SISD IGTG CLSS LENL RLPT LREE SSPR ELED SSGD QGRC GPTH QGSE DPSM LSQA QSAT EVEE RHVS PSCS TSRE RPFQ AGEL ILAE TGEG ETKF KKLF RLNN FGLL NSNW GAVP FGKI VGKF PGQI LRSS FGKQ YMLR RPAL EDYV VLMK RGTA ITFP KDIN MILS MMDI NPGD TV |
| 遺伝子ID: | 55006 |
| Uniprot: | Q9BVS5 |
| セルラーロケーション: | Mitochondrion |
| 計算された分子量: | 52kDa |
| 観察された分子量: | 52kDa |
| 同義語: | TRMT61B |
| バックグラウンド: |
| UniProt Protein Function: | Methyltransferase that catalyzes the formation of N1-methyladenine at position 58 (m1A58) in various tRNAs in mitochondrion, including tRNA(Leu) (deciphering codons UUA or UUG), tRNA(Lys) and tRNA(Ser) (deciphering codons UCA, UCU, UCG or UCC) (PubMed:23097428). Catalyzes the formation of 1-methyladenosine at position 947 of mitochondrial 16S ribosomal RNA and this modification is most likely important for mitoribosomal structure and function (PubMed:27631568). In addition to tRNA N1-methyltransferase activity, also acts as a mRNA N1-methyltransferase by mediating methylation of adenosine residues at the N1 position of MT-ND5 mRNA, leading to interfere with mitochondrial translation (PubMed:29107537). |
| UniProt Code: | Q9BVS5 |
| NCBI GenInfo Identifier: | 222831587 |
| NCBI Gene ID: | 55006 |
| NCBI Accession: | NP_060380.3 |
| UniProt Secondary Accession: | Q9BVS5,Q9H0Q9, Q9NWS7, |
| UniProt Related Accession: | Q9BVS5 |
| Molecular Weight: | 52,965 Da |
| NCBI Full Name: | tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial |
| NCBI Synonym Full Names: | tRNA methyltransferase 61B |
| NCBI Official Symbol: | TRMT61B |
| NCBI Protein Information: | tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial |
| UniProt Protein Name: | tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial |
| UniProt Synonym Protein Names: | mRNA methyladenosine-N(1)-methyltransferase |
| Protein Family: | tRNA (adenine(58)-N(1))-methyltransferase |
| UniProt Gene Name: | TRMT61B |
 | Western blot analysis of extracts of mouse liver, using TRMT61B antibody (CAB8067) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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