Anti-TRMT2A Antibody (CAB5975)
- SKU:
- CAB5975
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TRMT2A Antibody |
| 抗体コード: | CAB5975 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human TRMT2A (NP_073564.3). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:1000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, HeLa, K-562 |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human TRMT2A (NP_073564.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LASQ HLVA ILDP PRAG LHSK VILA IRRA KNLR RLLY VSCN PRAA MGNF VDLC RAPS NRVK GIPF RPVK AVAV DLFP QTPH CEML ILFE RVEH PNGT GVLG PHSP PAQP TPGP PDNT LQET GTFP SS |
| 遺伝子ID: | 27037 |
| Uniprot: | Q8IZ69 |
| セルラーロケーション: | |
| 計算された分子量: | 61kDa/68kDa |
| 観察された分子量: | 70kDa |
| 同義語: | TRMT2A, HTF9C |
| バックグラウンド: | The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene. |
| UniProt Protein Function: | HTF9C: May be involved in nucleic acid metabolism and/or modifications. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 22q11.21 Molecular Function:nucleotide binding; RNA methyltransferase activity Biological Process: RNA processing; RNA methylation |
| NCBI Summary: | The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| UniProt Code: | Q8IZ69 |
| NCBI GenInfo Identifier: | 51316479 |
| NCBI Gene ID: | 27037 |
| NCBI Accession: | Q8IZ69.2 |
| UniProt Secondary Accession: | Q8IZ69,Q32P57, Q96ME6, Q9H732, D3DX25, |
| UniProt Related Accession: | Q8IZ69 |
| Molecular Weight: | 625 |
| NCBI Full Name: | tRNA (uracil-5-)-methyltransferase homolog A |
| NCBI Synonym Full Names: | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| NCBI Official Symbol: | TRMT2A |
| NCBI Official Synonym Symbols: | HTF9C |
| NCBI Protein Information: | tRNA (uracil-5-)-methyltransferase homolog A; tRNA (uracil-5-)-methyltransferase homolog A; hpaII tiny fragments locus 9c protein; TRM2 tRNA methyltransferase 2 homolog A |
| UniProt Protein Name: | tRNA (uracil-5-)-methyltransferase homolog A |
| UniProt Synonym Protein Names: | HpaII tiny fragments locus 9c protein |
| Protein Family: | tRNA |
| UniProt Gene Name: | TRMT2A |
| UniProt Entry Name: | TRM2A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TRMT2A antibody (CAB5975) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat kidney using TRMT2A antibody (CAB5975) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human esophagus using TRMT2A antibody (CAB5975) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse stomach using TRMT2A antibody (CAB5975) at dilution of 1:100 (40x lens). |
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