Anti-TRHDE Antibody (CAB10300)

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SKU:
CAB10300
Product type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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Description

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抗体名:Anti-TRHDE Antibody
抗体コード:CAB10300
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 62-200 of human TRHDE (NP_037513.1).
申し込み:WB
推奨希釈:WB 1:200 - 1:2000
反応性:Human
ポジティブサンプル:22Rv1
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 62-200 of human TRHDE (NP_037513.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:SLRF DECG ASAT PGAD GGPS GFPE RGGN GSLP GSAR RNHH AGGD SWQP EAGG VASP GTTS AQPP SEEE REPW EPWT QLRL SGHL KPLH YNLM LTAF MENF TFSG EVNV EIAC RNAT RYVV LHAS RVAV EKVQ LAED RAF
遺伝子ID:29953
Uniprot:Q9UKU6
セルラーロケーション:Membrane, Single-pass type II membrane protein
計算された分子量:117kDa
観察された分子量:117kDa
同義語:TRHDE, PAP-II, PGPEP2, TRH-DE
バックグラウンド:This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.
UniProt Protein Function:TRHDE: Specific inactivation of TRH after its release. Belongs to the peptidase M1 family.
UniProt Protein Details:

Protein type:EC 3.4.19.6; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 12q21.1

Cellular Component: cytoplasm; integral to plasma membrane

Molecular Function:aminopeptidase activity; peptide binding; zinc ion binding

Biological Process: cell-cell signaling; peptide catabolic process; regulation of blood pressure; signal transduction

NCBI Summary:This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.[provided by RefSeq, Dec 2008]
UniProt Code:Q9UKU6
NCBI GenInfo Identifier:11387208
NCBI Gene ID:29953
NCBI Accession:Q9UKU6.1
UniProt Secondary Accession:Q9UKU6,Q6UWJ4, A5PL19,
UniProt Related Accession:Q9UKU6
Molecular Weight:117kDa
NCBI Full Name:Thyrotropin-releasing hormone-degrading ectoenzyme
NCBI Synonym Full Names:thyrotropin releasing hormone degrading enzyme
NCBI Official Symbol:TRHDE  
NCBI Official Synonym Symbols:PAP-II; PGPEP2; TRH-DE  
NCBI Protein Information:thyrotropin-releasing hormone-degrading ectoenzyme
UniProt Protein Name:Thyrotropin-releasing hormone-degrading ectoenzyme
UniProt Synonym Protein Names:Pyroglutamyl-peptidase II; PAP-II; TRH-specific aminopeptidase; Thyroliberinase
Protein Family:Thyrotropin-releasing hormone-degrading ectoenzyme
UniProt Gene Name:TRHDE  
Anti-TRHDE Antibody (CAB10300)Western blot analysis of extracts of 22Rv1 cells, using TRHDE antibody (CAB10300) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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