Anti-TRAM1 Antibody (CAB15142)
- SKU:
- CAB15142
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-TRAM1 Antibody |
| 抗体コード: | CAB15142 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 305-374 of human TRAM1 (NP_055109.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-251MG, mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 305-374 of human TRAM1 (NP_055109.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | CVTQ AFMM WKFI NFQL RRWR EHSA FQAP AVKK KPTV TKGR SSKK GTEN GVNG TLTS NVAD SPRN KKEK SS |
| 遺伝子ID: | 23471 |
| Uniprot: | Q15629 |
| セルラーロケーション: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
| 計算された分子量: | 39kDa/43kDa |
| 観察された分子量: | 45kDa |
| 同義語: | TRAM1, PNAS8, TRAM, TRAMP |
| バックグラウンド: | This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause. |
| UniProt Protein Function: | TRAM1: Stimulatory or required for the translocation of secretory proteins across the ER membrane. Belongs to the TRAM family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, misc.; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 8q13.3 Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane Molecular Function:protein binding; receptor activity Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; viral reproduction; gene expression; cotranslational protein targeting to membrane |
| NCBI Summary: | This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause. [provided by RefSeq, Oct 2009] |
| UniProt Code: | Q15629 |
| NCBI GenInfo Identifier: | 18202507 |
| NCBI Gene ID: | 23471 |
| NCBI Accession: | Q15629.3 |
| UniProt Related Accession: | Q15629 |
| Molecular Weight: | |
| NCBI Full Name: | Translocating chain-associated membrane protein 1 |
| NCBI Synonym Full Names: | translocation associated membrane protein 1 |
| NCBI Official Symbol: | TRAM1 |
| NCBI Official Synonym Symbols: | TRAM; PNAS8; TRAMP |
| NCBI Protein Information: | translocating chain-associated membrane protein 1 |
| UniProt Protein Name: | Translocating chain-associated membrane protein 1 |
| Protein Family: | Translocating chain-associated membrane protein |
| UniProt Gene Name: | TRAM1 |
| UniProt Entry Name: | TRAM1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TRAM1 antibody (CAB15142) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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