Anti-TOB1 Antibody (CAB14835)
- SKU:
- CAB14835
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-TOB1 Antibody |
抗体コード: | CAB14835 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TOB1 (NP_005740.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | HeLa, Mouse liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TOB1 (NP_005740.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MQLE IQVA LNFI ISYL YNKL PRRR VNIF GEEL ERLL KKKY EGHW YPEK PYKG SGFR CIHI GEKV DPVI EQAS KESG LDID DVRG NLPQ DLSV WIDP FEVS YQIG EKGP VKVL YVDD NNEN GCEL DKEI KNSF NPEA QVFM |
遺伝子ID: | 10140 |
Uniprot: | P50616 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 38kDa |
観察された分子量: | 38kDa |
同義語: | TOB1, APRO5, APRO6, PIG49, TOB, TROB, TROB1 |
バックグラウンド: | This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants. |
UniProt Protein Function: | TOB1: Anti-proliferative protein that interacts with the erbB- 2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors. Belongs to the BTG family. |
UniProt Protein Details: | Protein type:Adaptor/scaffold; Cell cycle regulation Chromosomal Location of Human Ortholog: 17q21 Cellular Component: CCR4-NOT complex Molecular Function:protein binding; receptor tyrosine kinase binding; SH3/SH2 adaptor activity Biological Process: negative regulation of cell proliferation; negative regulation of translation |
NCBI Summary: | This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
UniProt Code: | P50616 |
NCBI GenInfo Identifier: | 1729989 |
NCBI Gene ID: | 10140 |
NCBI Accession: | P50616.1 |
UniProt Secondary Accession: | P50616,Q4KMQ0, B2R9T0, D3DTY3, |
UniProt Related Accession: | P50616 |
Molecular Weight: | 38,155 Da |
NCBI Full Name: | Protein Tob1 |
NCBI Synonym Full Names: | transducer of ERBB2, 1 |
NCBI Official Symbol: | TOB1 |
NCBI Official Synonym Symbols: | TOB; TROB; APRO5; APRO6; PIG49; TROB1 |
NCBI Protein Information: | protein Tob1 |
UniProt Protein Name: | Protein Tob1 |
UniProt Synonym Protein Names: | Transducer of erbB-2 1 |
Protein Family: | Protein |
UniProt Gene Name: | TOB1 |
UniProt Entry Name: | TOB1_HUMAN |
View AllClose