Anti-THOP1 Antibody (CAB8756)
- SKU:
- CAB8756
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-THOP1 Antibody |
| 抗体コード: | CAB8756 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human THOP1 (NP_003240.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse skeletal muscle, Mouse heart, Mouse lung, Rat liver, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human THOP1 (NP_003240.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MKPP AACA GDMA DAAS PCSV VNDL RWDL SAQQ IEER TREL IEQT KRVY DQVG TQEF EDVS YEST LKAL ADVE VTYT VQRN ILDF PQHV SPSK DIRT ASTE ADKK LSEF DVEM SMRE DVYQ RIVW LQEK VQKD SLRP EAAR YLER LIKL GRRN GLHL PRET QENI KRIK KKLS LLCI DFNK NLNE DTTF LPFT LQEL GGLP EDFL NSLE KMED GKLK VTLK YPHY FPLL KKCH VPET RRKV EEAF NCRC KEEN CAIL KELV |
| 遺伝子ID: | 7064 |
| Uniprot: | P52888 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 28kDa/78kDa |
| 観察された分子量: | 79kDa |
| 同義語: | THOP1, EP24.15, MEPD_HUMAN, MP78, TOP |
| バックグラウンド: | The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. |
| NCBI Summary: | The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015] |
| UniProt Code: | P52888 |
| NCBI GenInfo Identifier: | 33878319 |
| NCBI Gene ID: | 7064 |
| NCBI Accession: | BC013878 |
| UniProt Secondary Accession: | P52888,Q9UCB3, B3KSE2, |
| UniProt Related Accession: | P52888 |
| Molecular Weight: | 28,908 Da |
| NCBI Full Name: | Homo sapiens thimet oligopeptidase 1, mRNA |
| NCBI Synonym Full Names: | thimet oligopeptidase 1 |
| NCBI Official Symbol: | THOP1 |
| NCBI Official Synonym Symbols: | TOP; MP78; EP24.15; MEPD_HUMAN |
| NCBI Protein Information: | thimet oligopeptidase |
| UniProt Protein Name: | Thimet oligopeptidase |
| UniProt Synonym Protein Names: | Endopeptidase 24.15; MP78 |
| Protein Family: | Thimet oligopeptidase |
| UniProt Gene Name: | THOP1 |
| UniProt Entry Name: | THOP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using THOP1 antibody (CAB8756) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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