Anti-SYT13 Antibody (CAB12852)
- SKU:
- CAB12852
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SYT13 Antibody |
| 抗体コード: | CAB12852 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-180 of human SYT13 (NP_065877.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-87MG, Mouse brain, Mouse heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-180 of human SYT13 (NP_065877.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | CRHM HPKK GLLP RDQD PDLE KAKP SLLG SAQQ FNVK KSTE PVQP RALL KFPD IYGP RPAV TAPE VINY ADYS LRST EEPT APAS PQPP NDSR LKRQ VTEE LFIL PQNG VVED VCVM ETWN PEKA ASWN QAPK LHYC LDYD CQKA ELFV TRL |
| 遺伝子ID: | 57586 |
| Uniprot: | Q7L8C5 |
| セルラーロケーション: | Membrane, Single-pass membrane protein |
| 計算された分子量: | 46kDa |
| 観察された分子量: | 47kDa |
| 同義語: | SYT13 |
| バックグラウンド: | This gene encodes a member of the large synaptotagmin protein family. Family members have an extracellular N-terminal transmembrane domain and a cytoplasmic C terminus with two tandem C2 domains (C2A and C2B). Synaptotogmin family members can form homo- and heteromeric complexes with each other. They also have different biochemical properties and developmental profiles, and patterns of tissue distribution. Synaptotagmins function as membrane traffickers in multicellular organisms. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. |
| UniProt Protein Function: | SYT13: May be involved in transport vesicle docking to the plasma membrane. Belongs to the synaptotagmin family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Vesicle Chromosomal Location of Human Ortholog: 11p11.2 Cellular Component: intracellular membrane-bound organelle; plasma membrane; transport vesicle Molecular Function:calcium ion binding; calcium-dependent phospholipid binding; clathrin binding; syntaxin binding Biological Process: calcium ion-dependent exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis; vesicle fusion |
| NCBI Summary: | This gene encodes a member of the large synaptotagmin protein family. Family members have an extracellular N-terminal transmembrane domain and a cytoplasmic C terminus with two tandem C2 domains (C2A and C2B). Synaptotogmin family members can form homo- and heteromeric complexes with each other. They also have different biochemical properties and developmental profiles, and patterns of tissue distribution. Synaptotagmins function as membrane traffickers in multicellular organisms. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q7L8C5 |
| NCBI GenInfo Identifier: | 74749900 |
| NCBI Gene ID: | 57586 |
| NCBI Accession: | Q7L8C5.1 |
| UniProt Secondary Accession: | Q7L8C5,Q9BQS3, Q9H041, Q9P2C0, A8K4P4, D3DQP1, |
| UniProt Related Accession: | Q7L8C5 |
| Molecular Weight: | 47kDa |
| NCBI Full Name: | Synaptotagmin-13 |
| NCBI Synonym Full Names: | synaptotagmin 13 |
| NCBI Official Symbol: | SYT13 |
| NCBI Protein Information: | synaptotagmin-13 |
| UniProt Protein Name: | Synaptotagmin-13 |
| UniProt Synonym Protein Names: | Synaptotagmin XIII; SytXIII |
| Protein Family: | Synaptotagmin |
| UniProt Gene Name: | SYT13 |
 | Western blot analysis of extracts of various cell lines, using SYT13 antibody (CAB12852) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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