Anti-ST3GAL1 Antibody (CAB11616)
- SKU:
- CAB11616
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ST3GAL1 Antibody |
| 抗体コード: | CAB11616 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-135 of human ST3GAL1 (NP_003024.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-135 of human ST3GAL1 (NP_003024.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | TTWF PKQM VLEL SENL KRLI KHRP CTCT HCIG QRKL SAWF DERF NQTM QPLL TAQN ALLE DDTY RWWL RLQR EKKP NNLN DTIK ELFR VVPG NVDP MLEK R |
| 遺伝子ID: | 6482 |
| Uniprot: | Q11201 |
| セルラーロケーション: | Golgi apparatus, Golgi stack membrane, Secreted, Single-pass type II membrane protein |
| 計算された分子量: | 39kDa |
| 観察された分子量: | 39kDa |
| 同義語: | ST3GAL1, Gal-NAc6S, SIAT4A, SIATFL, ST3GalA, ST3GalA.1, ST3GalIA, 1, ST3O |
| バックグラウンド: | The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. |
| UniProt Protein Function: | ST3GAL1: It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O- linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. Belongs to the glycosyltransferase 29 family. |
| UniProt Protein Details: | Protein type:EC 2.4.99.4; Membrane protein, integral; Glycan Metabolism - O-glycan biosynthesis; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Glycan Metabolism - glycosphingolipid biosynthesis - globo series; Glycan Metabolism - keratan sulfate biosynthesis; Transferase Chromosomal Location of Human Ortholog: 8q24.22 Cellular Component: Golgi membrane; membrane; integral to Golgi membrane Molecular Function:beta-galactoside alpha-2,3-sialyltransferase activity Biological Process: keratan sulfate metabolic process; protein amino acid O-linked glycosylation; cellular protein metabolic process; glycosaminoglycan metabolic process; dolichol-linked oligosaccharide biosynthetic process; O-glycan processing; keratan sulfate biosynthetic process; carbohydrate metabolic process; protein amino acid N-linked glycosylation; protein modification process; pathogenesis; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification; protein amino acid phosphorylation; N-acetylneuraminate metabolic process |
| NCBI Summary: | The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q11201 |
| NCBI GenInfo Identifier: | 1705559 |
| NCBI Gene ID: | 6482 |
| NCBI Accession: | Q11201.1 |
| UniProt Secondary Accession: | Q11201,O60677, Q9UN51, |
| UniProt Related Accession: | Q11201 |
| Molecular Weight: | 39,075 Da |
| NCBI Full Name: | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 |
| NCBI Synonym Full Names: | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| NCBI Official Symbol: | ST3GAL1 |
| NCBI Official Synonym Symbols: | ST3O; SIAT4A; SIATFL; ST3GalA; ST3GalIA; Gal-NAc6S; ST3GalA.1; ST3GalIA,1 |
| NCBI Protein Information: | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; SIAT4-A; ST3GalI; alpha 2,3-ST 1; beta-galactoside alpha-2,3-sialyltransferase 1; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; sialyltransferase 4A (beta-galactoside alpha-2,3-sialytransferase); sialyltransferase 4A (beta-galactoside alpha-2,3-sialyltransferase); sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase) |
| UniProt Protein Name: | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 |
| UniProt Synonym Protein Names: | Gal-NAc6S; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; SIATFL; ST3Gal I; ST3GalI; ST3GalA.1; ST3O; Sialyltransferase 4A; SIAT4-A |
| Protein Family: | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase |
| UniProt Gene Name: | ST3GAL1 |
| UniProt Entry Name: | SIA4A_HUMAN |
 | Western blot analysis of extracts of mouse liver, using ST3GAL1 antibody (CAB11616) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 40s. |
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