Anti-SSR3 Antibody (CAB17873)
- SKU:
- CAB17873
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-SSR3 Antibody |
| 抗体コード: | CAB17873 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-145 of human SSR3 (NP_009038.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Jurkat, K-562, BxPC-3, HeLa, mouse pancreas, mouse uterus, rat pancreas, rat uterus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-145 of human SSR3 (NP_009038.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | TYLV AFAY KNVK FVLK HKVA QKRE DAVS KEVT RKLS EADN RKMS RKEK DERI LWKK NEVA DYEA TTFS IFYN NTLF |
| 遺伝子ID: | 6747 |
| Uniprot: | Q9UNL2 |
| セルラーロケーション: | |
| 計算された分子量: | 21kDa |
| 観察された分子量: | 21kDa |
| 同義語: | TRAPG, SSR3 |
| バックグラウンド: | The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins/subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non-glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times. |
| UniProt Protein Function: | SSR3: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. Belongs to the TRAP-gamma family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 3q25.31 Cellular Component: integral to endoplasmic reticulum membrane; translocon complex Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; gene expression |
| NCBI Summary: | The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins/subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non-glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times. [provided by RefSeq, Aug 2010] |
| UniProt Code: | Q9UNL2 |
| NCBI GenInfo Identifier: | 9087205 |
| NCBI Gene ID: | 6747 |
| NCBI Accession: | Q9UNL2.1 |
| UniProt Related Accession: | Q9UNL2 |
| Molecular Weight: | 21kDa |
| NCBI Full Name: | Translocon-associated protein subunit gamma |
| NCBI Synonym Full Names: | signal sequence receptor subunit 3 |
| NCBI Official Symbol: | SSR3 |
| NCBI Official Synonym Symbols: | TRAPG |
| NCBI Protein Information: | translocon-associated protein subunit gamma |
| UniProt Protein Name: | Translocon-associated protein subunit gamma |
| UniProt Synonym Protein Names: | Signal sequence receptor subunit gamma; SSR-gamma |
| Protein Family: | SWI/SNF and RSC complexes |
| UniProt Gene Name: | SSR3 |
| UniProt Entry Name: | SSRG_HUMAN |
 | Western blot analysis of extracts of various cells, using SSR3 antibody (CAB17873) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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