Anti-SLC6A18 Antibody (CAB12860)
- SKU:
- CAB12860
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-SLC6A18 Antibody |
| 抗体コード: | CAB12860 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 310-400 of human SLC6A18 (NP_872438.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, Mouse kidney, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 310-400 of human SLC6A18 (NP_872438.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VLGF KATN DYEH CLDR NILS LIND FDFP EQSI SRDD YPAV LMHL NATW PKRV AQLP LKAC LLED FLDK SASG PGLA FVVF TETD LHMP GAP |
| 遺伝子ID: | 348932 |
| Uniprot: | Q96N87 |
| セルラーロケーション: | Membrane, Multi-pass membrane protein |
| 計算された分子量: | 70kDa |
| 観察された分子量: | 71kDa |
| 同義語: | SLC6A18, Xtrp2 |
| バックグラウンド: |
| UniProt Protein Function: | SLC6A18: Functions as a sodium and chloride-dependent neutral amino acid transporter. Genetic variations in SLC6A18 might contribute to the disease phentotype in some individuals with iminoglycinuria or hyperglycinuria, that carry variants in SLC36A2, SLC6A19 or SLC6A20. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A18 subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 5p15.33 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:amino acid transmembrane transporter activity; transporter activity Biological Process: amino acid transport; transport |
| NCBI Summary: | The SLC6 family of proteins, which includes SLC6A18, act as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Apr 2010] |
| UniProt Code: | Q96N87 |
| NCBI GenInfo Identifier: | 313104185 |
| NCBI Gene ID: | 348932 |
| NCBI Accession: | Q96N87.2 |
| UniProt Related Accession: | Q96N87 |
| Molecular Weight: | 71kDa |
| NCBI Full Name: | Sodium-dependent neutral amino acid transporter B(0)AT3 |
| NCBI Synonym Full Names: | solute carrier family 6 member 18 |
| NCBI Official Symbol: | SLC6A18 |
| NCBI Official Synonym Symbols: | Xtrp2 |
| NCBI Protein Information: | sodium-dependent neutral amino acid transporter B(0)AT3 |
| UniProt Protein Name: | Sodium-dependent neutral amino acid transporter B(0)AT3 |
| UniProt Synonym Protein Names: | Sodium- and chloride-dependent transporter XTRP2; Solute carrier family 6 member 18; System B(0) neutral amino acid transporter AT3 |
| UniProt Gene Name: | SLC6A18 |
 | Western blot analysis of extracts of various cell lines, using SLC6A18 antibody (CAB12860) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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