Anti-SLC23A1 Antibody (CAB10276)
- SKU:
- CAB10276
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-SLC23A1 Antibody |
| 抗体コード: | CAB10276 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 512-598 of human SLC23A1 (NP_005838.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | 293T, A-549, SKOV3, LO2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 512-598 of human SLC23A1 (NP_005838.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DNTV PGSP EERG LIQW KAGA HANS DMSS SLKS YDFP IGMG IVKR ITFL KYIP ICPV FKGF SSSS KDQI AIPE DTPE NTET ASVC TKV |
| 遺伝子ID: | 9963 |
| Uniprot: | Q9UHI7 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 28kDa/64kDa/65kDa |
| 観察された分子量: | 80kDa |
| 同義語: | SLC23A1, SLC23A2, SVCT1, YSPL3 |
| バックグラウンド: | The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | SLC23A1: Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transporter; Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 5q31.2 Cellular Component: apical plasma membrane; cytoplasm; integral to plasma membrane; intracellular organelle; membrane; plasma membrane Molecular Function:dehydroascorbic acid transporter activity; L-ascorbate:sodium symporter activity; L-ascorbic acid transporter activity; nucleobase transmembrane transporter activity; protein binding; sodium ion transmembrane transporter activity Biological Process: brain development; L-ascorbic acid metabolic process; L-ascorbic acid transport; nucleobase transport; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; response to toxin; sodium ion transport |
| NCBI Summary: | The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
| UniProt Code: | Q9UHI7 |
| NCBI GenInfo Identifier: | 296452969 |
| NCBI Gene ID: | 9963 |
| NCBI Accession: | Q9UHI7.3 |
| UniProt Secondary Accession: | Q9UHI7,O95191, Q8WWB6, Q9UGH4, Q9UI39, |
| UniProt Related Accession: | Q9UHI7 |
| Molecular Weight: | 28,531 Da |
| NCBI Full Name: | Solute carrier family 23 member 1 |
| NCBI Synonym Full Names: | solute carrier family 23 member 1 |
| NCBI Official Symbol: | SLC23A1 |
| NCBI Official Synonym Symbols: | SVCT1; YSPL3; SLC23A2 |
| NCBI Protein Information: | solute carrier family 23 member 1 |
| UniProt Protein Name: | Solute carrier family 23 member 1 |
| UniProt Synonym Protein Names: | Na(+)/L-ascorbic acid transporter 1; Sodium-dependent vitamin C transporter 1; hSVCT1; Yolk sac permease-like molecule 3 |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC23A1 |
| UniProt Entry Name: | S23A1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLC23A1 antibody (CAB10276) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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