Anti-SLC22A3/OCT3 Antibody (CAB19758)
- SKU:
- CAB19758
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- EMT
- Synonyms:
- EMTH
- Synonyms:
- OCT3
Frequently bought together:
Description
| I抗体名: | SLC22A3/OCT3 Rabbit mAb |
| 抗体コード: | CAB19758 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | EMT, EMTH, OCT3 |
| 申し込み: | WB, IHC |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human SLC22A3/OCT3 |
| 申し込み: | WB, IHC |
| 推奨される希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | PC-3, Mouse liver |
| 免疫原: | A synthesized peptide derived from human SLC22A3/OCT3 |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 6581 |
| Uniprot: | O75751 |
| 計算された分子量: | 75kDa |
| 観察された分子量: | 61KDa |
| UniProt Protein Function: | SLC22A3: Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 6q25.3 Cellular Component: membrane; integral to plasma membrane; plasma membrane Molecular Function:protein binding; toxin transporter activity; organic cation transmembrane transporter activity; dopamine transmembrane transporter activity; quaternary ammonium group transmembrane transporter activity Biological Process: dopamine transport; organic cation transport; histamine uptake; quaternary ammonium group transport; regulation of appetite; multidrug transport; transmembrane transport |
| NCBI Summary: | Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75751 |
| NCBI GenInfo Identifier: | 11415038 |
| NCBI Gene ID: | 6581 |
| NCBI Accession: | NP_068812.1 |
| UniProt Related Accession: | O75751 |
| Molecular Weight: | |
| NCBI Full Name: | solute carrier family 22 member 3 |
| NCBI Synonym Full Names: | solute carrier family 22 member 3 |
| NCBI Official Symbol: | SLC22A3 |
| NCBI Official Synonym Symbols: | EMT; EMTH; OCT3 |
| NCBI Protein Information: | solute carrier family 22 member 3 |
| UniProt Protein Name: | Solute carrier family 22 member 3 |
| UniProt Synonym Protein Names: | Extraneuronal monoamine transporter; EMT; Organic cation transporter 3 |
| UniProt Gene Name: | SLC22A3 |
| UniProt Entry Name: | S22A3_HUMAN |