Anti-SIRT3 Antibody (CAB5419)
- SKU:
- CAB5419
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SIRT3 Antibody |
| 抗体コード: | CAB5419 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-130 of human SIRT3 (NP_036371.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse liver, Mouse kidney, Mouse brain, Mouse heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-130 of human SIRT3 (NP_036371.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | ERVE AGGG VGPF QACG CRLV LGGR DDVS AGLR GSHG ARGE PLDP ARPL QRPP RPEV PRAF RRQP RAAA PSFF FSSI KGGR RSIS FSVG ASSV VGSG GSSD KGKL SLQD VAE |
| 遺伝子ID: | 23410 |
| Uniprot: | Q9NTG7 |
| セルラーロケーション: | Mitochondrion matrix |
| 計算された分子量: | 28kDa/43kDa |
| 観察された分子量: | 30kDa |
| 同義語: | SIRT3, SIR2L3, sirtuin 3 |
| バックグラウンド: | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. |
| UniProt Code: | Q9NTG7 |
| NCBI GenInfo Identifier: | 38258651 |
| NCBI Gene ID: | 23410 |
| NCBI Accession: | Q9NTG7.2 |
| UniProt Secondary Accession: | Q9NTG7,Q9Y6E8, B7Z5U6, |
| UniProt Related Accession: | Q9NTG7 |
| Molecular Weight: | 399 |
| NCBI Full Name: | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
| NCBI Synonym Full Names: | sirtuin 3 |
| NCBI Official Symbol: | SIRT3 |
| NCBI Official Synonym Symbols: | SIR2L3 |
| NCBI Protein Information: | NAD-dependent protein deacetylase sirtuin-3, mitochondrial; sir2-like 3; sirtuin type 3; SIR2-like protein 3; regulatory protein SIR2 homolog 3; NAD-dependent deacetylase sirtuin-3, mitochondrial; silent mating type information regulation 2, S.cerevisiae, homolog 3; mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase |
| UniProt Protein Name: | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
| UniProt Synonym Protein Names: | Regulatory protein SIR2 homolog 3; SIR2-like protein 3 |
| Protein Family: | NAD-dependent protein deacetylase sirtuin |
| UniProt Gene Name: | SIRT3 |
| UniProt Entry Name: | SIR3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SIRT3 antibody (CAB5419) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human prostate using SIRT3 antibody (CAB5419) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human esophagus using SIRT3 antibody (CAB5419) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using SIRT3 antibody (CAB5419) at dilution of 1:100 (40x lens). |
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