Anti-SERPINB5 Antibody (CAB1179)
- SKU:
- CAB1179
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SERPINB5 Antibody |
| 抗体コード: | CAB1179 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-189 of human SERPINB5 (NP_002630.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | NCI-H460, HT-29, HepG2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-189 of human SERPINB5 (NP_002630.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | EKEP LGNV LFSP ICLS TSLS LAQV GAKG DTAN EIGQ VLHF ENVK DVPF GFQT VTSD VNKL SSFY SLKL IKRL YVDK SLNL STEF ISST KRPY AKEL ETVD FKDK LEET KGQI NNSI KDLT DGHF ENIL ADNS VNDQ TKIL VVNA AYFV GKWM KKFS ESET KECP FRVN K |
| 遺伝子ID: | 5268 |
| Uniprot: | P36952 |
| セルラーロケーション: | Secreted, extracellular space |
| 計算された分子量: | 25kDa/42kDa |
| 観察された分子量: | 42kDa |
| 同義語: | SERPINB5, PI5, maspin, serpin B5 |
| バックグラウンド: |
| UniProt Protein Function: | maspin: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. Interacts with IRF6. Normal mammary epithelial cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 18q21.33 Cellular Component: extracellular space; cytoplasm Molecular Function:serine-type endopeptidase inhibitor activity; protein binding Biological Process: extracellular matrix organization and biogenesis; morphogenesis of an epithelium; cell motility; regulation of epithelial cell proliferation |
| UniProt Code: | P36952 |
| NCBI GenInfo Identifier: | 229462757 |
| NCBI Gene ID: | 5268 |
| NCBI Accession: | P36952.2 |
| UniProt Secondary Accession: | P36952,Q6N0B4, Q8WW89, B2R6Y4, |
| UniProt Related Accession: | P36952 |
| Molecular Weight: | 25,763 Da |
| NCBI Full Name: | Serpin B5 |
| NCBI Synonym Full Names: | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| NCBI Official Symbol: | SERPINB5 |
| NCBI Official Synonym Symbols: | PI5; maspin |
| NCBI Protein Information: | serpin B5; PI-5; peptidase inhibitor 5; protease inhibitor 5 (maspin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5 |
| UniProt Protein Name: | Serpin B5 |
| UniProt Synonym Protein Names: | Maspin; Peptidase inhibitor 5; PI-5 |
| Protein Family: | Serpin |
| UniProt Gene Name: | SERPINB5 |
| UniProt Entry Name: | SPB5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SERPINB5 antibody (CAB1179) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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