Anti-SARNP Antibody (CAB13701)
- SKU:
- CAB13701
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-SARNP Antibody |
| 抗体コード: | CAB13701 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SARNP (NP_149073.1). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: | 293T, HepG2, BxPC-3, U-87MG, MCF7 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SARNP (NP_149073.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MATE TVEL HKLK LAEL KQEC LARG LETK GIKQ DLIH RLQA YLEE HAEE EANE EDVL GDET EEEE TKPI ELPV KEEE PPEK TVDV AAEK KVVK ITSE IPQT ERMQ KRAE RFNV PVSL ESKK AARA ARFG ISSV PTKG LSSD NKPM VNLD KLKE RAQR FGLN VSSI SRKS EDDE KLKK RKER FGIV TSSA GTGT TEDT EAKK RKRA ERFG IA |
| 遺伝子ID: | 84324 |
| Uniprot: | P82979 |
| セルラーロケーション: | Nucleus, Nucleus speckle |
| 計算された分子量: | 23kDa |
| 観察された分子量: | 29kDa |
| 同義語: | SARNP, CIP29, HCC1, HSPC316, THO1 |
| バックグラウンド: | This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. |
| UniProt Protein Function: | CIP29: Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment region DNA. Also binds single- stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 12q13.2 Cellular Component: nucleoplasm; intracellular membrane-bound organelle; nuclear speck; nucleus Molecular Function:DNA binding Biological Process: regulation of translation; mRNA export from nucleus; transcription, DNA-dependent; regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009] |
| UniProt Code: | P82979 |
| NCBI GenInfo Identifier: | 18202440 |
| NCBI Gene ID: | 84324 |
| NCBI Accession: | P82979.3 |
| UniProt Secondary Accession: | P82979,Q9P066, A8K393, |
| UniProt Related Accession: | P82979 |
| Molecular Weight: | 210 |
| NCBI Full Name: | SAP domain-containing ribonucleoprotein |
| NCBI Synonym Full Names: | SAP domain containing ribonucleoprotein |
| NCBI Official Symbol: | SARNP |
| NCBI Official Synonym Symbols: | HCC1; THO1; CIP29; HSPC316 |
| NCBI Protein Information: | SAP domain-containing ribonucleoprotein; nuclear protein Hcc-1; hepatocellular carcinoma 1; cytokine induced protein 29 kDa; cytokine-induced protein of 29 kDa; proliferation associated cytokine-inducible protein CIP29; proliferation-associated cytokine-inducible protein CIP29 |
| UniProt Protein Name: | SAP domain-containing ribonucleoprotein |
| UniProt Synonym Protein Names: | Cytokine-induced protein of 29 kDa; Nuclear protein Hcc-1; Proliferation-associated cytokine-inducible protein CIP29 |
| Protein Family: | SAP domain-containing ribonucleoprotein |
| UniProt Gene Name: | SARNP |
| UniProt Entry Name: | SARNP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SARNP antibody (CAB13701) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded Human colon using SARNP Rabbit pAb (CAB13701) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of U-2 OS cells using SARNP antibody (CAB13701) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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