Anti-S100A7 Antibody (CAB1940)
- SKU:
- CAB1940
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-S100A7 Antibody |
| 抗体コード: | CAB1940 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human S100A7 (NP_002954.2). |
| 申し込み: | IHC |
| 推奨希釈: | IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human S100A7 (NP_002954.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSNT QAER SIIG MIDM FHKY TRRD DKIE KPSL LTMM KENF PNFL SACD KKGT NYLA DVFE KKDK NEDK KIDF SEFL SLLG DIAT DYHK QSHG AAPC SGGS Q |
| 遺伝子ID: | 6278 |
| Uniprot: | P31151 |
| セルラーロケーション: | Cytoplasm, Secreted |
| 計算された分子量: | 11kDa |
| 観察された分子量: |
| 同義語: | S100A7, PSOR1, S100A7c |
| バックグラウンド: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. |
| UniProt Protein Function: | S100A7: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q21 Cellular Component: focal adhesion; endoplasmic reticulum; cytoplasm; extracellular region; nucleus; cytosol Molecular Function:RAGE receptor binding; protein binding; zinc ion binding; calcium ion binding Biological Process: keratinocyte differentiation; sequestering of metal ion; response to reactive oxygen species; epidermis development; innate immune response; response to lipopolysaccharide; angiogenesis; defense response to Gram-negative bacterium |
| NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014] |
| UniProt Code: | P31151 |
| NCBI GenInfo Identifier: | 172046820 |
| NCBI Gene ID: | 6278 |
| NCBI Accession: | P31151.4 |
| UniProt Secondary Accession: | P31151,Q5SY67, Q6FGE3, Q9H1E2, |
| UniProt Related Accession: | P31151 |
| Molecular Weight: | 101 |
| NCBI Full Name: | Protein S100-A7 |
| NCBI Synonym Full Names: | S100 calcium binding protein A7 |
| NCBI Official Symbol: | S100A7 |
| NCBI Official Synonym Symbols: | PSOR1; S100A7c |
| NCBI Protein Information: | protein S100-A7; psoriasin 1; S100 calcium-binding protein A7 (psoriasin 1) |
| UniProt Protein Name: | Protein S100-A7 |
| UniProt Synonym Protein Names: | Psoriasin; S100 calcium-binding protein A7 |
| Protein Family: | Protein |
| UniProt Gene Name: | S100A7 |
| UniProt Entry Name: | S10A7_HUMAN |
 | Immunohistochemistry of paraffin-embedded rat lung using S100A7 antibody (CAB1940) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human esophagus using S100A7 antibody (CAB1940) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse lung using S100A7 antibody (CAB1940) at dilution of 1:100 (40x lens). |
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