Anti-RIOX2 Antibody (RACO0147)
- SKU:
- RACO0147
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- ELISA
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 商品名: | RIOX2 Antibody |
| Product SKU: | RACO0147 |
| サイズ: | 50ul |
| 宿主種: | Human |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | A synthesized peptide derived from human RIOX2 |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | Affinity-chromatography |
| 抗体のクローン性: | Monoclonal |
| アイソタイプ: | Rabbit IgG |
| Conjugate: | Non-conjugated |
| バックグラウンド: | Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
| シノニム: | Ribosomal oxygenase 2, 60S ribosomal protein L27a histidine hydroxylase, Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA, Histone lysine demethylase MINA, MYC-induced nuclear antigen, Mineral dust-induced gene protein, Nucleolar protein 52, Ribosomal oxygenase MINA, ROX, RIOX2 |
| UniProt Protein Function: | MINA: Involved in cellular proliferation. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. Belongs to the MINA53/NO66 family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 3q11.2 Cellular Component: transcription factor complex; cytoplasm; nucleolus; cytosol; nucleus Molecular Function:dioxygenase activity; metal ion binding Biological Process: transcription, DNA-dependent; ribosome biogenesis and assembly; negative regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]).[supplied by OMIM, May 2008] |
| UniProt Code: | Q8IUF8 |
| NCBI GenInfo Identifier: | 74750624 |
| NCBI Gene ID: | 84864 |
| NCBI Accession: | Q8IUF8.1 |
| UniProt Related Accession: | Q8IUF8 |
| Molecular Weight: | |
| NCBI Full Name: | Ribosomal oxygenase 2 |
| NCBI Synonym Full Names: | ribosomal oxygenase 2 |
| NCBI Official Symbol: | RIOX2 |
| NCBI Official Synonym Symbols: | ROX; MDIG; MINA; NO52; JMJD10; MINA53 |
| NCBI Protein Information: | ribosomal oxygenase 2 |
| UniProt Protein Name: | Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA |
| UniProt Synonym Protein Names: | 60S ribosomal protein L27a histidine hydroxylase; Histone lysine demethylase MINA; MYC-induced nuclear antigen; Mineral dust-induced gene protein; Nucleolar protein 52; Ribosomal oxygenase MINA; ROX |
| Protein Family: | Bifunctional lysine-specific demethylase and histidyl-hydroxylase |
| UniProt Gene Name: | MINA |
| UniProt Entry Name: | MINA_HUMAN |