Anti-RELT Antibody (CAB15540)
- SKU:
- CAB15540
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| 抗体名: | Anti-RELT Antibody |
| 抗体コード: | CAB15540 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-162 of human RELT (NP_116260.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Raji, K-562, LO2, Mouse thymus, Mouse brain, Rat thymus, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-162 of human RELT (NP_116260.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | STTL WQCP PGEE PDLD PGQG TLCR PCPP GTFS AAWG SSPC QPHA RCSL WRRL EAQV GMAT RDTL CGDC WPGW FGPW GVPR VPCQ PCSW APLG THGC DEWG RRAR RGVE VAAG ASSG GETR QPGN GTRA GGPE ETAA Q |
| 遺伝子ID: | 84957 |
| Uniprot: | Q969Z4 |
| セルラーロケーション: | Cell membrane, Cytoplasm, Single-pass type I membrane protein |
| 計算された分子量: | 46kDa |
| 観察された分子量: | 47kDa |
| 同義語: | RELT, TNFRSF19L, TRLT |
| バックグラウンド: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. |
| UniProt Protein Function: | RELT: Mediates activation of NF-kappa-B. May play a role in T- cell activation. Belongs to the RELT family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 11q13.4 Cellular Component: integral to plasma membrane Molecular Function:tumor necrosis factor receptor activity Biological Process: immune response; inflammatory response; multicellular organismal development; positive regulation of MAPKKK cascade; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide |
| NCBI Summary: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q969Z4 |
| NCBI GenInfo Identifier: | 21264092 |
| NCBI Gene ID: | 84957 |
| NCBI Accession: | Q969Z4.1 |
| UniProt Secondary Accession: | Q969Z4,Q86V34, Q96JU1, Q9BUX7, |
| UniProt Related Accession: | Q969Z4 |
| Molecular Weight: | 46,092 Da |
| NCBI Full Name: | Tumor necrosis factor receptor superfamily member 19L |
| NCBI Synonym Full Names: | RELT tumor necrosis factor receptor |
| NCBI Official Symbol: | RELT |
| NCBI Official Synonym Symbols: | TRLT; TNFRSF19L |
| NCBI Protein Information: | tumor necrosis factor receptor superfamily member 19L |
| UniProt Protein Name: | Tumor necrosis factor receptor superfamily member 19L |
| UniProt Synonym Protein Names: | Receptor expressed in lymphoid tissues |
| Protein Family: | RELT-like protein |
| UniProt Gene Name: | RELT |
| UniProt Entry Name: | TR19L_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RELT antibody (CAB15540) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60S. |
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