Anti-RAB11B Antibody (CAB15350)
- SKU:
- CAB15350
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RAB11B Antibody |
| 抗体コード: | CAB15350 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-215 of human RAB11B (NP_004209.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse pancreas |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-215 of human RAB11B (NP_004209.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | HLRA VPTD EARA FAEK NNLS FIET SALD STNV EEAF KNIL TEIY RIVS QKQI ADRA AHDE SPGN NVVD ISVP PTTD GQKP NKLQ CC |
| 遺伝子ID: | 9230 |
| Uniprot: | Q15907 |
| セルラーロケーション: | Cytoplasmic side, Cytoplasmic vesicle, Lipid-anchor, Recycling endosome membrane, phagosome membrane, secretory vesicle, synaptic vesicle membrane |
| 計算された分子量: | 19kDa/24kDa |
| 観察された分子量: | 24kDa |
| 同義語: | RAB11B, H-YPT3 |
| バックグラウンド: | The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010] |
| UniProt Protein Function: | RAB11B: GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis. Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4. Belongs to the small GTPase superfamily. Rab family. |
| UniProt Protein Details: | Protein type:G protein, monomeric, Rab; G protein, monomeric; G protein Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: synaptic vesicle; recycling endosome; phagocytic vesicle membrane; synaptic vesicle membrane; mitochondrion; recycling endosome membrane; phagocytic vesicle; cell junction Molecular Function:GTPase activity; protein binding; GDP binding; GTP binding; myosin V binding Biological Process: receptor recycling; intracellular protein transport; regulated secretory pathway; constitutive secretory pathway; transferrin transport; Rab protein signal transduction; melanosome transport |
| NCBI Summary: | The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010] |
| UniProt Code: | Q15907 |
| NCBI GenInfo Identifier: | 38258938 |
| NCBI Gene ID: | 9230 |
| NCBI Accession: | Q15907.4 |
| UniProt Secondary Accession: | Q15907,Q2YDT2, Q5U0I1, Q6FHR0, Q6FI42, Q8NI07, A5YM50 B2R7I4, B4DMK0, D6W671, |
| UniProt Related Accession: | Q15907 |
| Molecular Weight: | 218 |
| NCBI Full Name: | Ras-related protein Rab-11B |
| NCBI Synonym Full Names: | RAB11B, member RAS oncogene family |
| NCBI Official Symbol: | RAB11B |
| NCBI Official Synonym Symbols: | H-YPT3 |
| NCBI Protein Information: | ras-related protein Rab-11B; GTP-binding protein YPT3; RAB11B, member of RAS oncogene family |
| UniProt Protein Name: | Ras-related protein Rab-11B |
| UniProt Synonym Protein Names: | GTP-binding protein YPT3 |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB11B |
| UniProt Entry Name: | RB11B_HUMAN |
 | Western blot analysis of extracts of Mouse pancreas, using RAB11B antibody (CAB15350) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 120s. |
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