Anti-PRPH Antibody (CAB4048)
- SKU:
- CAB4048
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PRPH Antibody |
| 抗体コード: | CAB4048 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PRPH (NP_006253.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:20 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-251MG, HepG2, MCF7, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PRPH (NP_006253.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSHH PSGL RAGF SSTS YRRT FGPP PSLS PGAF SYSS SSRF SSSR LLGS ASPS SSVR LGSF RSPR AGAG ALLR LPSE RLDF SMAE ALNQ EFLA TRSN EKQE LQEL NDRF ANFI EKVR FLEQ QNAA LRGE LSQA RGQE PARA DQLC QQEL RELR RELE LLGR ERDR VQVE RDGL AEDL AALK QRLE EETR KRED AEHN LVLF RKDV DDAT LSRL ELER KIES LMDE IEFL KKLH EEEL RDLQ VSVE SQQV QQVE VEAT VKPE |
| 遺伝子ID: | 5630 |
| Uniprot: | P41219 |
| セルラーロケーション: | |
| 計算された分子量: | 53kDa |
| 観察された分子量: | 54-62kDa |
| 同義語: | PRPH, NEF4, PRPH1 |
| バックグラウンド: | This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis. |
| UniProt Protein Function: | peripherin: Class-III neuronal intermediate filament protein. Belongs to the intermediate filament family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 12q12-q13 Cellular Component: membrane; type III intermediate filament; neurofilament; intermediate filament Molecular Function:structural molecule activity Biological Process: intermediate filament cytoskeleton organization and biogenesis Disease: Amyotrophic Lateral Sclerosis 1 |
| NCBI Summary: | This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P41219 |
| NCBI GenInfo Identifier: | 118585871 |
| NCBI Gene ID: | 5630 |
| NCBI Accession: | P41219.2 |
| UniProt Secondary Accession: | P41219,Q8N577, |
| UniProt Related Accession: | P41219 |
| Molecular Weight: | 470 |
| NCBI Full Name: | Peripherin |
| NCBI Synonym Full Names: | peripherin |
| NCBI Official Symbol: | PRPH |
| NCBI Official Synonym Symbols: | NEF4; PRPH1 |
| NCBI Protein Information: | peripherin; neurofilament 4 (57kD) |
| UniProt Protein Name: | Peripherin |
| UniProt Synonym Protein Names: | Neurofilament 4 |
| Protein Family: | Peripherin |
| UniProt Gene Name: | PRPH |
| UniProt Entry Name: | PERI_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PRPH antibody (CAB4048) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat heart using PRPH antibody (CAB4048) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse heart using PRPH antibody (CAB4048) at dilution of 1:100 (40x lens). |
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