Anti-PRICKLE2 Antibody (CAB8023)
- SKU:
- CAB8023
- Product type:
- Antibody
- Application:
- WB
- Application:
- IF
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | PRICKLE2 Rabbit Polyclonal Antibody |
抗体コード: | CAB8023 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 615-844 of human PRICKLE2 (NP_942559.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse brain, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 615-844 of human PRICKLE2 (NP_942559.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | QEME GNLH QLSN PIGY RDLQ SHGR MHQS FDFD GGMA GSKL PGQE GVRI QPMS ERTR RRAT SRDD NRRF RPHR SRRS RRSR SDNA LHLA SERE AISR LKDR PPLR ARED YDQF MRQR SFQE SMGH GSRR DLYG QCPR TVSD LALQ NAFG DRWG PYFA EYDW CSTC SSSS ESDN EGYF LGEP IPQP ARLR YVTS DELL HKYS SYGL PKSS TLGG RGQL HSRK RQKS KNCI IS |
遺伝子ID: | 166336 |
Uniprot: | Q7Z3G6 |
セルラーロケーション: | Nucleus membrane |
計算された分子量: | 95kDa |
観察された分子量: | 126kDa |
同義語: | PRICKLE2, EPM5 |
バックグラウンド: | This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. |
UniProt Protein Function: | PRICKLE2: Defects in PRICKLE2 are the cause of progressive myoclonic epilepsy type 5 (EPM5). EPM5 is a neurodegenerative disorder characterized by myoclonic seizures and variable neurologic symptoms including cognitive decline and persistent movement abnormalities. Belongs to the prickle / espinas / testin family. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 3p14.1 Cellular Component: nuclear membrane; apicolateral plasma membrane; cytoplasm; lateral plasma membrane Molecular Function:zinc ion binding Biological Process: establishment and/or maintenance of epithelial cell polarity; neurite development Disease: Epilepsy, Progressive Myoclonic 5 |
NCBI Summary: | This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q7Z3G6 |
NCBI GenInfo Identifier: | 38524620 |
NCBI Gene ID: | 166336 |
NCBI Accession: | NP_942559 |
UniProt Related Accession: | Q7Z3G6 |
Molecular Weight: | 95kDa |
NCBI Full Name: | prickle-like protein 2 |
NCBI Synonym Full Names: | prickle planar cell polarity protein 2 |
NCBI Official Symbol: | PRICKLE2 |
NCBI Official Synonym Symbols: | EPM5 |
NCBI Protein Information: | prickle-like protein 2 |
UniProt Protein Name: | Prickle-like protein 2 |
Protein Family: | Prickle-like protein |
UniProt Gene Name: | PRICKLE2 |
UniProt Entry Name: | PRIC2_HUMAN |
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