Anti-PPP2R3B Antibody (CAB8489)
- SKU:
- CAB8489
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PPP2R3B Antibody |
| 抗体コード: | CAB8489 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 356-575 of human PPP2R3B (NP_037371.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HeLa, SW620, BT-474, SKOV3, mouse skeletal muscle |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 356-575 of human PPP2R3B (NP_037371.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | FSGA VTRG RKVQ KEGK ISYA DFVW FLIS EEDK KTPT SIEY WFRC MDLD GDGA LSMF ELEY FYEE QCRR LDSM AIEA LPFQ DCLC QMLD LVKP RTEG KITL QDLK RCKL ANVF FDTF FNIE KYLD HEQK EQIS LLRD GDSG GPEL SDWE KYAA EEYD ILVA EETA GEPW EDGF EAEL SPVE QKLS ALRS PLAQ RPFF EAPS PLGA VDLY EYAC GDED LEPL |
| 遺伝子ID: | 28227 |
| Uniprot: | Q9Y5P8 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 20kDa/65kDa |
| 観察された分子量: | 80kDa |
| 同義語: | PPP2R3B, NYREN8, PPP2R3L, PPP2R3LY, PR48, PR70 |
| バックグラウンド: | Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. |
| UniProt Protein Function: | PPP2R3B: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit Chromosomal Location of Human Ortholog: Xp22.33; Yp11.3 Cellular Component: nucleoplasm; nucleus; protein phosphatase type 2A complex Molecular Function:phosphoprotein phosphatase activity; protein binding; protein phosphatase type 2A regulator activity; protein serine/threonine phosphatase activity Biological Process: cell cycle arrest; protein amino acid dephosphorylation |
| NCBI Summary: | Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq, Apr 2010] |
| UniProt Code: | Q9Y5P8 |
| NCBI GenInfo Identifier: | 158523346 |
| NCBI Gene ID: | 28227 |
| NCBI Accession: | Q9Y5P8.2 |
| UniProt Secondary Accession: | Q9Y5P8,Q6P4G9, Q7RTT1, Q96H01, |
| UniProt Related Accession: | Q9Y5P8 |
| Molecular Weight: | 20,111 Da |
| NCBI Full Name: | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta |
| NCBI Synonym Full Names: | protein phosphatase 2 regulatory subunit B''beta |
| NCBI Official Symbol: | PPP2R3B |
| NCBI Official Synonym Symbols: | PR48; NYREN8; PPP2R3L; PPP2R3LY |
| NCBI Protein Information: | serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta |
| UniProt Protein Name: | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta |
| UniProt Synonym Protein Names: | PP2A subunit B isoform PR48; Protein phosphatase 2A 48 kDa regulatory subunit |
| Protein Family: | Serine/threonine-protein phosphatase |
| UniProt Gene Name: | PPP2R3B |
| UniProt Entry Name: | P2R3B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PPP2R3B antibody (CAB8489) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
 | Western blot analysis of extracts of mouse skeletal muscle, using PPP2R3B antibody (CAB8489) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
View AllClose